Sauerbrei Andreas
Institute of Virology and Antiviral Therapy, German Consulting Laboratory for Herpes Simplex Virus and Varicella-Zoster Virus, Jena University Hospital, Friedrich-Schiller University of Jena, Jena, Germany.
Infect Drug Resist. 2016 Jun 13;9:129-41. doi: 10.2147/IDR.S96164. eCollection 2016.
As one of the most common sexually transmitted diseases, genital herpes is a global medical problem with significant physical and psychological morbidity. Genital herpes is caused by herpes simplex virus type 1 or type 2 and can manifest as primary and/or recurrent infection. This manuscript provides an overview about the fundamental knowledge on the virus, its epidemiology, and infection. Furthermore, the current possibilities of antiviral therapeutic interventions and laboratory diagnosis of genital herpes as well as the present situation and perspectives for the treatment by novel antivirals and prevention of disease by vaccination are presented. Since the medical management of patients with genital herpes simplex virus infection is often unsatisfactory, this review aims at all physicians and health professionals who are involved in the care of patients with genital herpes. The information provided would help to improve the counseling of affected patients and to optimize the diagnosis, treatment, and prevention of this particular disease.
作为最常见的性传播疾病之一，生殖器疱疹是一个全球性的医学问题，会导致严重的身心疾病。生殖器疱疹由1型或2型单纯疱疹病毒引起，可表现为原发性和/或复发性感染。本文提供了关于该病毒的基础知识、流行病学及感染情况的概述。此外，还介绍了生殖器疱疹抗病毒治疗干预措施和实验室诊断的当前可能性，以及新型抗病毒药物治疗和疫苗预防疾病的现状与前景。由于单纯疱疹病毒感染患者的医疗管理往往不尽人意，本综述面向所有参与生殖器疱疹患者护理的医生和卫生专业人员。所提供的信息将有助于改善对受影响患者的咨询，并优化这种特定疾病的诊断、治疗和预防。
