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红细胞输血中影响组织氧合的因素。

Factors Affecting Tissue Oxygenation in Erythrocyte Transfusions.

作者信息

Aykut Güçlü, Yürük Koray, İnce Can

机构信息

Department of Intensive Care, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands; Department of Anaesthesiology, University Hospital Heidelberg, Heidelberg, Germany.

Department of Intensive Care, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.

出版信息

Turk J Anaesthesiol Reanim. 2014 Jun;42(3):111-6. doi: 10.5152/TJAR.2014.112014. Epub 2014 Jun 1.

DOI:10.5152/TJAR.2014.112014
PMID:27366403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4894217/
Abstract

Red blood cell transfusions are used to increase the oxygen-carrying capacity of blood in anemic states. But, because of the changes during storage of blood components and the specifics of preparation, erythrocytes may have controversial effects on tissue oxygenation and microcirculation. Also, the patient situation may play a role in the differing responses in oxygenation and microcirculation. In this review, the studies concerning the effects of banked blood and patient characteristics on microcirculation and tissue oxygenation are summarized.

摘要

红细胞输血用于增加贫血状态下血液的携氧能力。但是,由于血液成分储存过程中的变化以及制备的特殊性,红细胞可能对组织氧合和微循环产生有争议的影响。此外,患者情况可能在氧合和微循环的不同反应中起作用。在本综述中,总结了关于库存血和患者特征对微循环及组织氧合影响的研究。

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1
Factors Affecting Tissue Oxygenation in Erythrocyte Transfusions.红细胞输血中影响组织氧合的因素。
Turk J Anaesthesiol Reanim. 2014 Jun;42(3):111-6. doi: 10.5152/TJAR.2014.112014. Epub 2014 Jun 1.
2
The effects of non-leukoreduced red blood cell transfusions on microcirculation in mixed surgical patients.非白细胞滤除红细胞输注对混合手术患者微循环的影响。
Transfus Apher Sci. 2013 Oct;49(2):212-22. doi: 10.1016/j.transci.2013.01.016. Epub 2013 Feb 9.
3
Effects of fresh versus banked blood transfusions on microcirculatory hemodynamics and tissue oxygenation in the rat cremaster model.新鲜血与库存血输血对大鼠提睾肌模型微循环血流动力学及组织氧合的影响。
Surgery. 2007 May;141(5):630-9. doi: 10.1016/j.surg.2006.09.015.
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Role of storage time of red blood cells on microcirculation and tissue oxygenation in critically ill patients.红细胞储存时间对危重症患者微循环及组织氧合的作用
Curr Opin Anaesthesiol. 2009 Apr;22(2):275-80. doi: 10.1097/ACO.0b013e328323f7c4.
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The impact of red blood cell storage duration on tissue oxygenation in cardiac surgery.红细胞储存时间对心脏手术组织氧合的影响。
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Oxygenating the microcirculation: the perspective from blood transfusion and blood storage.微循环的氧合作用:输血与血液储存的视角
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Microcirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in patients with sepsis: a pilot study.脓毒症患者输注去白细胞或未去白细胞红细胞的微循环效应:一项初步研究。
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The Effects of red Blood Cell Transfusion on Tissue Oxygenation and the Microcirculation in the Intensive Care Unit: A Systematic Review.《红细胞输血对重症监护病房组织氧合和微循环的影响:系统评价》。
Transfus Med Rev. 2017 Oct;31(4):205-222. doi: 10.1016/j.tmrv.2017.07.003. Epub 2017 Jul 21.

本文引用的文献

1
The effects of non-leukoreduced red blood cell transfusions on microcirculation in mixed surgical patients.非白细胞滤除红细胞输注对混合手术患者微循环的影响。
Transfus Apher Sci. 2013 Oct;49(2):212-22. doi: 10.1016/j.transci.2013.01.016. Epub 2013 Feb 9.
2
Transfusion of banked red blood cells and the effects on hemorrheology and microvascular hemodynamics in anemic hematology outpatients.储存式红细胞输注及其对贫血血液科门诊患者血液流变学和微血管血液动力学的影响。
Transfusion. 2013 Jun;53(6):1346-52. doi: 10.1111/j.1537-2995.2012.03905.x. Epub 2012 Sep 24.
3
Red blood cell transfusions and tissue oxygenation in anemic hematology outpatients.贫血血液病门诊患者的红细胞输注与组织氧合。
Transfusion. 2012 Mar;52(3):641-6. doi: 10.1111/j.1537-2995.2011.03312.x. Epub 2011 Aug 29.
4
Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion.红细胞微粒和无细胞血红蛋白清除一氧化氮作为红细胞储存损伤的机制。
Circulation. 2011 Jul 26;124(4):465-76. doi: 10.1161/CIRCULATIONAHA.110.008698. Epub 2011 Jul 11.
5
Blood transfusions recruit the microcirculation during cardiac surgery.输血在心脏手术中募集微循环。
Transfusion. 2011 May;51(5):961-7. doi: 10.1111/j.1537-2995.2010.02971.x. Epub 2010 Dec 6.
6
Red cell changes during storage.储存期间红细胞的变化。
Transfus Apher Sci. 2010 Aug;43(1):51-9. doi: 10.1016/j.transci.2010.05.009. Epub 2010 Jun 16.
7
Anemia and blood transfusion in a surgical intensive care unit.外科重症监护病房的贫血与输血。
Crit Care. 2010;14(3):R92. doi: 10.1186/cc9026. Epub 2010 May 24.
8
The endothelium: physiological functions and role in microcirculatory failure during severe sepsis.内皮细胞:严重脓毒症时的生理功能及其在微循环衰竭中的作用。
Intensive Care Med. 2010 Aug;36(8):1286-98. doi: 10.1007/s00134-010-1893-6. Epub 2010 May 5.
9
Near-infrared spectroscopy technique to evaluate the effects of red blood cell transfusion on tissue oxygenation.近红外光谱技术评估红细胞输注对组织氧合的影响。
Crit Care. 2009;13 Suppl 5(Suppl 5):S11. doi: 10.1186/cc8009. Epub 2009 Nov 30.
10
Rejuvenation of stored human red blood cells reverses the renal microvascular oxygenation deficit in an isovolemic transfusion model in rats.储存人红细胞的复苏可逆转大鼠等容输血模型中的肾微血管氧合不足。
Transfusion. 2009 Mar;49(3):427-4. doi: 10.1111/j.1537-2995.2008.02002.x. Epub 2008 Nov 25.