红细胞输血中影响组织氧合的因素。
Factors Affecting Tissue Oxygenation in Erythrocyte Transfusions.
作者信息
Aykut Güçlü, Yürük Koray, İnce Can
机构信息
Department of Intensive Care, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands; Department of Anaesthesiology, University Hospital Heidelberg, Heidelberg, Germany.
Department of Intensive Care, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands.
出版信息
Turk J Anaesthesiol Reanim. 2014 Jun;42(3):111-6. doi: 10.5152/TJAR.2014.112014. Epub 2014 Jun 1.
Abstract
Red blood cell transfusions are used to increase the oxygen-carrying capacity of blood in anemic states. But, because of the changes during storage of blood components and the specifics of preparation, erythrocytes may have controversial effects on tissue oxygenation and microcirculation. Also, the patient situation may play a role in the differing responses in oxygenation and microcirculation. In this review, the studies concerning the effects of banked blood and patient characteristics on microcirculation and tissue oxygenation are summarized.
摘要
红细胞输血用于增加贫血状态下血液的携氧能力。但是，由于血液成分储存过程中的变化以及制备的特殊性，红细胞可能对组织氧合和微循环产生有争议的影响。此外，患者情况可能在氧合和微循环的不同反应中起作用。在本综述中，总结了关于库存血和患者特征对微循环及组织氧合影响的研究。
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本文引用的文献
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The effects of non-leukoreduced red blood cell transfusions on microcirculation in mixed surgical patients.非白细胞滤除红细胞输注对混合手术患者微循环的影响。
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2
Transfusion of banked red blood cells and the effects on hemorrheology and microvascular hemodynamics in anemic hematology outpatients.储存式红细胞输注及其对贫血血液科门诊患者血液流变学和微血管血液动力学的影响。
Transfusion. 2013 Jun;53(6):1346-52. doi: 10.1111/j.1537-2995.2012.03905.x. Epub 2012 Sep 24.
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Red blood cell transfusions and tissue oxygenation in anemic hematology outpatients.贫血血液病门诊患者的红细胞输注与组织氧合。
Transfusion. 2012 Mar;52(3):641-6. doi: 10.1111/j.1537-2995.2011.03312.x. Epub 2011 Aug 29.
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Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion.红细胞微粒和无细胞血红蛋白清除一氧化氮作为红细胞储存损伤的机制。
Circulation. 2011 Jul 26;124(4):465-76. doi: 10.1161/CIRCULATIONAHA.110.008698. Epub 2011 Jul 11.
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