Canullo Luigi, Dehner Jan Friedrich, Penarrocha David, Checchi Vittorio, Mazzoni Annalisa, Breschi Lorenzo
Private Practice, 00198 Rome, Italy; Department of Oral Surgery, University of Valencia, 46700 Valencia, Spain.
Department of Oral Surgery, Goethe-Universität Frankfurt am Main, 60311 Frankfurt, Germany.
Biomed Res Int. 2016;2016:2952530. doi: 10.1155/2016/2952530. Epub 2016 Jun 6.
The aim of this preliminary prospective RCT was to histologically evaluate peri-implant soft tissues around titanium abutments treated using different cleaning methods. Sixteen patients were randomized into three groups: laboratory customized abutments underwent Plasma of Argon treatment (Plasma Group), laboratory customized abutments underwent cleaning by steam (Steam Group), and abutments were used as they came from industry (Control Group). Seven days after the second surgery, soft tissues around abutments were harvested. Samples were histologically analyzed. Soft tissues surrounding Plasma Group abutments predominantly showed diffuse chronic infiltrate, almost no acute infiltrate, with presence of few polymorphonuclear neutrophil granulocytes, and a diffuse presence of collagenization bands. Similarly, in Steam Group, the histological analysis showed a high variability of inflammatory expression factors. Tissues harvested from Control Group showed presence of few neutrophil granulocytes, moderate presence of lymphocytes, and diffuse collagenization bands in some sections, while they showed absence of acute infiltrate in 40% of sections. However, no statistical difference was found among the tested groups for each parameter (p > 0.05). Within the limit of the present study, results showed no statistically significant difference concerning inflammation and healing tendency between test and control groups.
这项初步前瞻性随机对照试验的目的是从组织学角度评估使用不同清洁方法处理的钛基台周围的种植体周围软组织。16名患者被随机分为三组：实验室定制基台接受氩气等离子体处理（等离子体组），实验室定制基台接受蒸汽清洁（蒸汽组），基台按从厂家获得时的状态使用（对照组）。第二次手术后7天，采集基台周围的软组织。对样本进行组织学分析。等离子体组基台周围的软组织主要表现为弥漫性慢性浸润，几乎没有急性浸润，有少量多形核中性粒细胞，并有弥漫性胶原化带。同样，在蒸汽组中，组织学分析显示炎症表达因子的变异性很高。从对照组采集的组织显示有少量中性粒细胞，淋巴细胞中度存在，部分切片中有弥漫性胶原化带，而40%的切片中没有急性浸润。然而，在每个参数上，测试组之间未发现统计学差异（p>0.05）。在本研究的范围内，结果显示测试组和对照组在炎症和愈合倾向方面没有统计学上的显著差异。
