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一名43岁女性意外动脉内注射苯妥英钠。

An accidental intra-arterial injection of phenytoin in a 43-year-old woman.

作者信息

Khan Z H, Faghihnassiri S

机构信息

Department of Anesthesiology and Critical Care, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran 14197-33141, Iran.

出版信息

Saudi J Anaesth. 2016 Jul-Sep;10(3):342-4. doi: 10.4103/1658-354X.174916.

DOI:10.4103/1658-354X.174916
PMID:27375394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4916823/
Abstract

We report an accidental intra-arterial injection of phenytoin in a 43-year-old woman undergoing ventriculoperitoneal shunt for hydrocephalus. To flush the arterial line with heparin, mistakenly phenytoin was injected which caused cutaneous gangrene along the radial side of the forearm and an absence of pulsation in the radial artery. After flushing the artery with normal saline and lidocaine, the patient was transferred to the Intensive Care Unit. There the patient was put on intravenous heparin that resolved the problem leading to complete recovery of the patient. The case is being reported to emphasize the importance of close surveillance in injecting drugs through the arterial line access.

摘要

我们报告了一例在一名43岁因脑积水接受脑室腹腔分流术的女性患者中意外发生的动脉内注射苯妥英钠事件。为用肝素冲洗动脉管路,误注入了苯妥英钠,导致前臂桡侧皮肤坏疽以及桡动脉搏动消失。在用生理盐水和利多卡因冲洗动脉后,患者被转至重症监护病房。在那里,患者接受了静脉注射肝素治疗,问题得以解决,患者完全康复。报告该病例是为强调通过动脉管路通路注射药物时密切监测的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25ba/4916823/ada082b07ca4/SJA-10-342-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25ba/4916823/636301276378/SJA-10-342-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25ba/4916823/ada082b07ca4/SJA-10-342-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25ba/4916823/636301276378/SJA-10-342-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25ba/4916823/ada082b07ca4/SJA-10-342-g002.jpg

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本文引用的文献

1
Tissue necrosis of hand caused by phenytoin extravasation: An unusual occurrence.苯妥英钠外渗导致手部组织坏死:一种罕见情况。
Saudi J Anaesth. 2014 Apr;8(2):309-10. doi: 10.4103/1658-354X.130766.
2
Purple glove syndrome: A looming threat.紫手套综合征:一个潜在的威胁。
J Neurosci Rural Pract. 2010 Jul;1(2):121-2. doi: 10.4103/0976-3147.71732.
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Radial artery thrombosis following transradial coronary angiography: incidence and rationale for treatment of symptomatic patients with low-molecular-weight heparins.经桡动脉冠状动脉造影术后桡动脉血栓形成:采用低分子肝素治疗有症状患者的发生率和治疗原理。
Clin Res Cardiol. 2010 Dec;99(12):841-7. doi: 10.1007/s00392-010-0197-8. Epub 2010 Jul 13.
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Extravasation injury of the upper extremity by intravenous phenytoin.静脉注射苯妥英钠导致的上肢外渗性损伤。
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Digital gangrene after accidental intra-arterial injection of phenytoin (epanutin).苯妥英钠(大仑丁)意外动脉内注射后发生的指端坏疽
Eur J Surg. 1992 May;158(5):315-6.