Tulay Koca Tuba, Emrullah Tanrikut, Aydin Arslan, Ciledag Ozdemir Filiz
Koca Tuba Tülay, Medical Doctor, Dept. of Physical Medicine and Rehabilitation, State Hospital, Malatya, Turkey.
Tanrikut Emrullah, Operator Doctor, Dept. of Obstetrics and Gynecology, State Hospital, Malatya, Turkey.
Pak J Med Sci. 2016 May-Jun;32(3):545-9. doi: 10.12669/pjms.323.9574.
Fibromyalgia syndrome (FS) is a chronic pain disorder usually affecting women in their fertile period of life. However, the relationship between FS and pregnancy has not been studied in depth. The effect of FS on the course of pregnancy is poorly investigated in the current literature. Here we aimed to investigate the effects of FS to menarche age, gravidity, parity and duration of breastfeeding.
One hundred and eighty-seven non-pregnant females attending between March 2015-June 2015, to Malatya State Hospital Physical Medicine and Rehabilitation Outpatient Clinic, were included in this prospective study. One hundred eleven (111) of them were diagnosed with FS according to the American Rheumatology Association (ACR) 2010 criteria and were defined as group 1; group 2 comprised of seventy six (76) non-pregnant healthy volunteers. All participants were asked about their menarche age, marriage age, gravidity, parity, duration of breastfeeding by conducting a basic questionnaire survey. Patients' body mass index (BMI) were recorded. Depression parameters were evaluated by Beck Depression Scale (BDS).
The average age of the patients was 39.04±9.21 (FS) and 38.47±9.65 (Control) years; first menarche age was at 13.28±1.38 (FS) and 13.59±1.54 years (Control), and marriage age was 20.1±3.62 (FS) and 20.69±3.90 years (Control), respectively. No statistically significant difference was found (p=0.598) between BMI values (FS, 27.76±4.95; Control 26.90±4.56 kg/m(2)). The results from both groups were similar in terms of gravidity, parity, and breastfeeding duration, with no statistically significant differences (p=0.252, 0.093, 0.075, respectively). The only significant difference was found in the depression parameter. The BDS results were statistically different between the groups, found higher in FS group (p=0.000).
FS occurs as a result of symptoms such as mood disorder, anxiety, cognitive and sleep disorders, and also hormonal changes; no exact cause has yet been established. The syndrome usually occurs during fertile period of young female. According to the findings of our study, FS has no negative effect on the outcome of gravidity, parity, and duration of breastfeeding in Turkish women. Further studies about the effects of FS on the course of pregnancy are required.
纤维肌痛综合征（FS）是一种慢性疼痛疾病，通常影响处于生育期的女性。然而，FS与妊娠之间的关系尚未得到深入研究。目前的文献对FS对妊娠过程的影响研究较少。在此，我们旨在研究FS对初潮年龄、妊娠次数、产次和母乳喂养持续时间的影响。
2015年3月至2015年6月期间到马拉蒂亚州立医院物理医学与康复门诊就诊的187名未怀孕女性被纳入这项前瞻性研究。其中111人根据美国风湿病学会（ACR）2010年标准被诊断为FS，被定义为第1组；第2组由76名未怀孕的健康志愿者组成。通过进行基本问卷调查，询问所有参与者的初潮年龄、结婚年龄、妊娠次数、产次、母乳喂养持续时间。记录患者的体重指数（BMI）。通过贝克抑郁量表（BDS）评估抑郁参数。
患者的平均年龄为39.04±9.21岁（FS组）和38.47±9.65岁（对照组）；初潮年龄分别为13.28±1.38岁（FS组）和13.59±1.54岁（对照组），结婚年龄分别为20.1±3.62岁（FS组）和20.69±3.90岁（对照组）。BMI值之间未发现统计学显著差异（p = 0.598）（FS组为27.76±4.95；对照组为26.90±4.56 kg/m²）。两组在妊娠次数、产次和母乳喂养持续时间方面的结果相似，无统计学显著差异（分别为p = 0.252、0.093、0.075）。唯一的显著差异出现在抑郁参数方面。两组之间BDS结果存在统计学差异，FS组更高（p = 0.000）。
FS是由情绪障碍、焦虑、认知和睡眠障碍以及激素变化等症状引起的，确切病因尚未确定。该综合征通常发生在年轻女性的生育期。根据我们的研究结果，FS对土耳其女性的妊娠结局、产次和母乳喂养持续时间没有负面影响。需要进一步研究FS对妊娠过程 的影响。
