Jonas J B, Gusek G C, Nguyen N X, Naumann G O
Fortschr Ophthalmol. 1989;86(2):92-4.
Glaucomatous optic nerve damage is associated with changes in the parapapillary region. These changes were measured on 15 degrees color stereo slides of the optic nerve head. We examined 450 eyes of 330 patients suffering from chronic primary open-angle glaucoma and 200 eyes of 161 normal subjects. The glaucoma group was divided into five stages according to the neuroretinal rim configuration. In the parapapillary region, the "alpha" zone characterized by irregular hypo- and hyperpigmentation, and the "beta" zone (large visible choroidal vessels and visible sclera) were differentiated. Zone "beta" was located between the optic disc and zone "alpha". Both zones were significantly larger in the total glaucoma group (p less than 0.00001, Mann-Whitney-test), and in each of the five glaucoma stages, than in the normal subjects. Zone "beta" increased in size more than zone "alpha". The parapapillary region deserves special attention in the diagnosis of glaucoma.
青光眼性视神经损伤与视乳头旁区域的变化有关。这些变化是在视神经乳头的15度彩色立体幻灯片上测量的。我们检查了330例慢性原发性开角型青光眼患者的450只眼睛和161名正常受试者的200只眼睛。青光眼组根据神经视网膜边缘形态分为五个阶段。在视乳头旁区域，区分出以不规则色素减退和色素沉着为特征的“α”区和（可见的大脉络膜血管和巩膜）“β”区。“β”区位于视盘和“α”区之间。在整个青光眼组（p<0.00001，曼-惠特尼检验）以及五个青光眼阶段中的每一个阶段，这两个区域均显著大于正常受试者。“β”区大小的增加超过“α”区。视乳头旁区域在青光眼诊断中值得特别关注。
