Montuori Mauro, Santurro Letizia, Feliziani Andrea, DE Sanctis Flavio, Ricciardi Edoardo, Gaudio Daniele, Campione Elena, Bianchi Luca, Silvi Maria B, Rossi Piero
Department of Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, Italy -
Department of Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, Italy.
G Ital Dermatol Venereol. 2018 Feb;153(1):19-25. doi: 10.23736/S0392-0488.16.05373-6. Epub 2016 Jul 5.
The aim of this study was to evaluate feasibility, safety and efficacy in day surgery of electrochemotherapy (ECT) using bleomycin in non-melanoma head and neck skin cancer.
We performed a prospective study on fifteen patients treated at the General Surgery Department at University Hospital of Tor Vergata, Rome between April 2011 and February 2013.
We observed 100% complete response evaluated with WHO criteria at 6 weeks after treatment. No partial response was achieved.
ECT is a simple, highly effective and safe treatment for head and neck non melanoma skin cancer. In our experience ECT can be performed safely in Day Surgery also in patients ASA III. Side effects associated with ECT are minimal and the treatment is well tolerated also by older patients, with minimal impairment of organ function and healthy tissues and with good esthetic results. We would encourage this treatment especially for older patients with multiple comorbidities, in which conventional surgical approach is not easily practicable.
本研究旨在评估使用博来霉素进行电化学疗法（ECT）治疗非黑色素瘤头颈皮肤癌在日间手术中的可行性、安全性和疗效。
我们对2011年4月至2013年2月期间在罗马第二大学医院普通外科接受治疗的15例患者进行了一项前瞻性研究。
治疗6周后，根据世界卫生组织标准评估，观察到完全缓解率为100%。未出现部分缓解情况。
ECT是治疗头颈非黑色素瘤皮肤癌的一种简单、高效且安全的方法。根据我们的经验，即使是ASA III级的患者，ECT也可在日间手术中安全进行。ECT相关的副作用极小，老年患者对该治疗的耐受性也良好，对器官功能和健康组织的损害最小，且美学效果良好。我们尤其鼓励对患有多种合并症、传统手术方法不易实施的老年患者采用这种治疗方法。
