Center for Algorithmic Biotechnology, Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia, 199034.
Department of Mathematics and Information Technology, St. Petersburg Academic University, Russian Academy of Sciences, St. Petersburg, Russia, 194021.
Bioinformatics. 2016 Nov 1;32(21):3321-3323. doi: 10.1093/bioinformatics/btw379. Epub 2016 Jul 4.
: Data visualization plays an increasingly important role in NGS data analysis. With advances in both sequencing and computational technologies, it has become a new bottleneck in genomics studies. Indeed, evaluation of de novo genome assemblies is one of the areas that can benefit from the visualization. However, even though multiple quality assessment methods are now available, existing visualization tools are hardly suitable for this purpose. Here, we present Icarus-a novel genome visualizer for accurate assessment and analysis of genomic draft assemblies, which is based on the tool QUAST. Icarus can be used in studies where a related reference genome is available, as well as for non-model organisms. The tool is available online and as a standalone application.
http://cab.spbu.ru/software/icarus CONTACT: aleksey.gurevich@spbu.ruSupplementary information: Supplementary data are available at Bioinformatics online.
数据可视化在 NGS 数据分析中起着越来越重要的作用。随着测序和计算技术的进步,它已成为基因组学研究中的一个新瓶颈。事实上,从头基因组组装的评估是可以从可视化中受益的领域之一。然而,尽管现在有多种质量评估方法,但现有的可视化工具几乎不适合这一目的。在这里,我们提出了 Icarus,这是一种用于准确评估和分析基因组草案组装的新型基因组可视化工具,它基于 QUAST 工具。Icarus 可用于有相关参考基因组的研究,也可用于非模式生物。该工具可在线使用,也可作为独立应用程序使用。
http://cab.spbu.ru/software/icarus
补充数据可在 Bioinformatics 在线获得。