与水痘带状疱疹病毒相关的灼口综合征。
Burning mouth syndrome associated with varicella zoster virus.
作者信息
Nagel Maria A, Gilden Don
机构信息
Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA.
出版信息
BMJ Case Rep. 2016 Jul 5;2016:bcr2016215953. doi: 10.1136/bcr-2016-215953.
Abstract
We present two cases of burning mouth syndrome (BMS)-of 8-month duration in a 61-year-old woman and of 2-year duration in a 63-year-old woman-both associated with increased levels of antivaricella zoster virus (VZV) IgM antibodies in serum and with pain that improved with antiviral treatment. Combined with our previous finding of BMS due to herpes simplex virus type 1 (HSV-1) infection, we recommend evaluation of patients with BMS not only for VZV or HSV-1 DNA in the saliva, but also for serum anti-VZV and anti-HSV-1 IgM antibodies. Both infections are treatable with oral antiviral agents.
摘要
我们报告了两例灼口综合征（BMS）病例，一例发生在一名61岁女性身上，病程8个月；另一例发生在一名63岁女性身上，病程2年。这两例均与血清中抗水痘带状疱疹病毒（VZV）IgM抗体水平升高有关，且疼痛经抗病毒治疗后有所改善。结合我们之前发现的1型单纯疱疹病毒（HSV-1）感染导致的BMS，我们建议对BMS患者不仅要检测唾液中的VZV或HSV-1 DNA，还要检测血清中的抗VZV和抗HSV-1 IgM抗体。这两种感染都可用口服抗病毒药物治疗。
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