富含血小板纤维蛋白在牙周组织再生中的应用
Platelet Rich Fibrin in Periodontal Regeneration.
作者信息
Arunachalam Muthukumaraswamy, Pulikkotil Shaju J, Sonia Nath
机构信息
Department of Periodontology and Oral Implantology, Tamilnadu Government Dental College, Chennai, India.
Department of Restorative Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.
出版信息
Open Dent J. 2016 May 11;10:174-81. doi: 10.2174/1874210601610010174. eCollection 2016.
Abstract
Periodontitis is a chronic bacterial infection resulting in destruction of the supporting structures of the teeth. Regeneration of the lost tissues has faced difficulties primarily due to the lack of support during the intricate healing processes. A surgical additive which can 'jump start' the healing process to a more predictable regenerative process is always on the wish list of any periodontist. Platelet-rich fibrin (PRF) is a second generation platelet concentrate that has been considered to be an important, easy to obtain, predictable surgical additive for periodontal regeneration. This autologous scaffold provides the much needed bio-chemical mediators which has the potential for enhancing reconstruction of the periodontium. This review article tries to understand as to why PRF would be an important link to reach predictable periodontal regeneration.
摘要
牙周炎是一种慢性细菌感染，会导致牙齿支持结构的破坏。由于在复杂的愈合过程中缺乏支持，丢失组织的再生面临困难。一种能够“启动”愈合过程，使其朝着更可预测的再生过程发展的手术添加剂，一直是每位牙周病医生梦寐以求的。富血小板纤维蛋白（PRF）是第二代血小板浓缩物，被认为是一种重要、易于获取且可预测的牙周再生手术添加剂。这种自体支架提供了急需的生化介质，具有促进牙周组织重建的潜力。这篇综述文章试图弄清楚为什么PRF会成为实现可预测牙周再生的重要环节。
相似文献
1
Platelet Rich Fibrin in Periodontal Regeneration.富含血小板纤维蛋白在牙周组织再生中的应用
Open Dent J. 2016 May 11;10:174-81. doi: 10.2174/1874210601610010174. eCollection 2016.
2
Autologous platelet-rich fibrin stimulates canine periodontal regeneration.富自体血小板纤维蛋白促进犬牙周组织再生。
Sci Rep. 2020 Feb 5;10(1):1850. doi: 10.1038/s41598-020-58732-x.
3
Platelet rich fibrin: a new paradigm in periodontal regeneration.富血小板纤维蛋白：牙周组织再生的新范例
Cell Tissue Bank. 2013 Sep;14(3):453-63. doi: 10.1007/s10561-012-9349-6. Epub 2012 Nov 11.
4
Platelet rich fibrin and alloplast in the treatment of intrabony defect.富血小板纤维蛋白与异体材料治疗骨内缺损
J Pharm Bioallied Sci. 2014 Apr;6(2):127-31. doi: 10.4103/0975-7406.129178.
5
Platelet-rich fibrin promotes periodontal regeneration and enhances alveolar bone augmentation.富血小板纤维蛋白促进牙周再生和增强牙槽骨增量。
Biomed Res Int. 2013;2013:638043. doi: 10.1155/2013/638043. Epub 2013 Mar 26.
6
Injectable Platelet-Rich Fibrin - A Revolution in Periodontal Regeneration.可注射富血小板纤维蛋白——牙周再生领域的一项革新。
Cureus. 2022 Aug 31;14(8):e28647. doi: 10.7759/cureus.28647. eCollection 2022 Aug.
7
Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 1: Periodontal and dentoalveolar surgery.用于口腔颌面外科的富血小板血浆（PRP）和富血小板纤维蛋白（PRF）的现有知识和观点第 1 部分：牙周和牙牙槽外科。
Curr Pharm Biotechnol. 2012 Jun;13(7):1207-30. doi: 10.2174/138920112800624391.
8
Effects of platelet-rich fibrin on human gingival and periodontal ligament fibroblast proliferation from chronic periodontitis versus periodontally healthy subjects.富血小板纤维蛋白对慢性牙周炎和牙周健康患者人牙龈和牙周韧带成纤维细胞增殖的影响。
Clin Exp Dent Res. 2021 Aug;7(4):436-442. doi: 10.1002/cre2.370. Epub 2021 Jan 14.
9
Platelet-Rich Fibrin Combined With a Porous Hydroxyapatite Graft for the Treatment of 3-Wall Intrabony Defects in Chronic Periodontitis: A Randomized Controlled Clinical Trial.富血小板纤维蛋白联合多孔羟基磷灰石移植物治疗慢性牙周炎三壁骨内缺损的随机对照临床试验。
J Periodontol. 2017 Dec;88(12):1288-1296. doi: 10.1902/jop.2012.110722.
10
Platelet-Rich Fibrin With 1.2% Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis: A Randomized Controlled Clinical Trial.富含血小板纤维蛋白联合1.2%瑞舒伐他汀治疗慢性牙周炎骨内缺损：一项随机对照临床试验
J Periodontol. 2016 Dec;87(12):1468-1473. doi: 10.1902/jop.2016.160015. Epub 2016 Jul 24.
引用本文的文献
1
A Novel Ultrastructural Morphological Characterization of Platelet-Rich Fibrin among Diabetics.糖尿病患者富血小板纤维蛋白的新型超微结构形态学特征
J Microsc Ultrastruct. 2023 Mar 22;13(1):25-31. doi: 10.4103/jmau.jmau_103_22. eCollection 2025 Jan-Mar.
2
Application of Platelet-Rich Fibrin as Regeneration Assistant in Immediate Auototransplantation of Third Molar with Unformed Roots: Case Report and Review of Literature.富含血小板纤维蛋白在未发育完全牙根的第三磨牙即刻自体移植中作为再生辅助剂的应用：病例报告及文献综述
Case Rep Dent. 2020 Jan 21;2020:8170646. doi: 10.1155/2020/8170646. eCollection 2020.
3
Platelet-Rich Fibrin as a Bone Graft Material in Oral and Maxillofacial Bone Regeneration: Classification and Summary for Better Application.富血小板纤维蛋白作为口腔颌面骨再生中的骨移植材料：更好应用的分类和总结。
Biomed Res Int. 2019 Dec 6;2019:3295756. doi: 10.1155/2019/3295756. eCollection 2019.
4
Novel Use of Silicone Sheets for Immediate Implant Placement in Fresh Molar Extraction Sockets.硅胶片在新鲜磨牙拔牙窝即刻种植中的新应用
Case Rep Dent. 2019 Feb 28;2019:3501671. doi: 10.1155/2019/3501671. eCollection 2019.
5
Use of Platelet Rich Plasma in the Management of Periodontal Intra-Osseous Defects: A Clinical Study.富血小板血浆在牙周骨内缺损治疗中的应用：一项临床研究。
J Int Soc Prev Community Dent. 2017 Mar-Apr;7(2):105-115. doi: 10.4103/jispcd.JISPCD_28_17. Epub 2017 Mar 29.
本文引用的文献
1
Platelet-Rich Fibrin Combined With a Porous Hydroxyapatite Graft for the Treatment of 3-Wall Intrabony Defects in Chronic Periodontitis: A Randomized Controlled Clinical Trial.富血小板纤维蛋白联合多孔羟基磷灰石移植物治疗慢性牙周炎三壁骨内缺损的随机对照临床试验。
J Periodontol. 2017 Dec;88(12):1288-1296. doi: 10.1902/jop.2012.110722.
2
Prevalence of periodontitis in the Indian population: A literature review.印度人群中牙周炎的患病率：文献综述。
J Indian Soc Periodontol. 2011 Jan;15(1):29-34. doi: 10.4103/0972-124X.82261.
3
Is platelet concentrate advantageous for the surgical treatment of periodontal diseases? A systematic review and meta-analysis.血小板浓缩物有利于牙周病的手术治疗吗？系统评价和荟萃分析。
J Periodontol. 2011 Aug;82(8):1100-11. doi: 10.1902/jop.2010.100605. Epub 2010 Dec 28.
4
Three-dimensional architecture and cell composition of a Choukroun's platelet-rich fibrin clot and membrane.邱泷氏富血小板纤维蛋白凝块和膜的三维结构和细胞组成。
J Periodontol. 2010 Apr;81(4):546-55. doi: 10.1902/jop.2009.090531.
5
Sinus floor augmentation with simultaneous implant placement using Choukroun's platelet-rich fibrin as the sole grafting material: a radiologic and histologic study at 6 months.应用 Choukroun 富血小板纤维蛋白作为唯一植骨材料同期进行种植体植入的牙槽嵴增高术：6 个月时的放射学和组织学研究。
J Periodontol. 2009 Dec;80(12):2056-64. doi: 10.1902/jop.2009.090252.
6
Applications of platelet-rich fibrin matrix in facial plastic surgery.富血小板纤维蛋白基质在面部整形手术中的应用。
Facial Plast Surg. 2009 Nov;25(4):270-6. doi: 10.1055/s-0029-1242033. Epub 2009 Nov 18.
7
A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro.富血小板纤维蛋白（PRF）与富血小板血浆（PRP）对大鼠成骨细胞体外增殖和分化影响的比较研究
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Nov;108(5):707-13. doi: 10.1016/j.tripleo.2009.06.044.
8
Platelet-poor plasma stimulates the proliferation but inhibits the differentiation of rat osteoblastic cells in vitro.
Clin Oral Implants Res. 2009 Jun;20(6):616-23. doi: 10.1111/j.1600-0501.2008.01687.x.
9
In vitro release of growth factors from platelet-rich fibrin (PRF): a proposal to optimize the clinical applications of PRF.富血小板纤维蛋白（PRF）中生长因子的体外释放：优化PRF临床应用的建议
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Jul;108(1):56-61. doi: 10.1016/j.tripleo.2009.02.004. Epub 2009 May 17.
10
The relevance of Choukroun's platelet-rich fibrin and metronidazole during complex maxillary rehabilitations using bone allograft. Part I: a new grafting protocol.在使用同种异体骨进行复杂上颌骨修复过程中Choukroun富血小板纤维蛋白与甲硝唑的相关性。第一部分：一种新的移植方案。
Implant Dent. 2009 Apr;18(2):102-11. doi: 10.1097/ID.0b013e318198cf00.
Zotero 插件