Arunachalam Muthukumaraswamy, Pulikkotil Shaju J, Sonia Nath
Department of Periodontology and Oral Implantology, Tamilnadu Government Dental College, Chennai, India.
Department of Restorative Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.
Open Dent J. 2016 May 11;10:174-81. doi: 10.2174/1874210601610010174. eCollection 2016.
Periodontitis is a chronic bacterial infection resulting in destruction of the supporting structures of the teeth. Regeneration of the lost tissues has faced difficulties primarily due to the lack of support during the intricate healing processes. A surgical additive which can 'jump start' the healing process to a more predictable regenerative process is always on the wish list of any periodontist. Platelet-rich fibrin (PRF) is a second generation platelet concentrate that has been considered to be an important, easy to obtain, predictable surgical additive for periodontal regeneration. This autologous scaffold provides the much needed bio-chemical mediators which has the potential for enhancing reconstruction of the periodontium. This review article tries to understand as to why PRF would be an important link to reach predictable periodontal regeneration.
牙周炎是一种慢性细菌感染，会导致牙齿支持结构的破坏。由于在复杂的愈合过程中缺乏支持，丢失组织的再生面临困难。一种能够“启动”愈合过程，使其朝着更可预测的再生过程发展的手术添加剂，一直是每位牙周病医生梦寐以求的。富血小板纤维蛋白（PRF）是第二代血小板浓缩物，被认为是一种重要、易于获取且可预测的牙周再生手术添加剂。这种自体支架提供了急需的生化介质，具有促进牙周组织重建的潜力。这篇综述文章试图弄清楚为什么PRF会成为实现可预测牙周再生的重要环节。
