由嘧啶-嘌呤DNA形成的独特结构，可能是四链的。
Unique structures formed by pyrimidine-purine DNAs which may be four-stranded.
作者信息
Johnson D, Morgan A R
出版信息
Proc Natl Acad Sci U S A. 1978 Apr;75(4):1637-41. doi: 10.1073/pnas.75.4.1637.
Abstract
Pyrimidine-purine DNAs with repeating sequences can be made to undergo a reversible transition to possibly a tetra-stranded complex. Physicochemical characterization of the new structures and model building are consistent with, in the case of d(TC)n-d(GA)n, a tetra-stranded complex forming by the addition of d(GA)n to the remaining space in the major groove of the triple-stranded complex d(TC)n-d(GA)n-d(CT)n. A possible role for tetra-stranded complexes in chromosome condensation is suggested by the natural occurrence of repeating sequence pyrimidine-purine DNAs and the properties of condensed chromosomes.
摘要
具有重复序列的嘧啶 - 嘌呤DNA可发生可逆转变，可能形成四链复合物。对于d(TC)n - d(GA)n而言，新结构的物理化学特征及模型构建与下述情况一致：通过在三链复合物d(TC)n - d(GA)n - d(CT)n大沟的剩余空间中添加d(GA)n形成四链复合物。重复序列嘧啶 - 嘌呤DNA的自然存在以及浓缩染色体的特性表明了四链复合物在染色体浓缩中可能发挥的作用。
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