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一项关于含柠檬酸锌和三氯生的牙膏维持牙龈健康功效的为期一年的研究。

One-year study of the efficacy of a dentifrice containing zinc citrate and triclosan to maintain gingival health.

作者信息

Svatun B, Saxton C A, Rölla G, van der Ouderaa F

机构信息

Unilever Dental Research, Port Sunlight Laboratory, Bebington, Wirral, England.

出版信息

Scand J Dent Res. 1989 Jun;97(3):242-6. doi: 10.1111/j.1600-0722.1989.tb01608.x.

Abstract

In a previous study we demonstrated that gingival health could be maintained in a group of highly motivated nurses using a dentifrice containing a zinc salt and triclosan. We have now investigated the effect of the experimental dentifrice on a group of less motivated men. One hundred and three male students were given oral hygiene instruction (OHI) and their teeth were professionally cleaned. For each individual, both the instruction and cleaning were completed in a single 15-min period. Two balanced groups were formed, based on the prestudy plaque levels and gingival bleeding. One group used the experimental dentifrice for 12 months, while the other used a control. Results were assessed after 6 months, and after 12 months. As a result of the OHI, plaque and gingival bleeding were reduced at the end of the prestudy period. This improvement was not maintained by the control group even for 6 months. In contrast, the test group exhibited significantly lower plaque levels and higher standard of gingival health throughout the 12 months. Reassessment of available participants 6 months after the study showed that gingival health in both groups had returned to its prestudy condition. The lower observed standard of gingival health in the test group after ceasing to use the experimental dentifrice further supports the conclusion that this dentifrice can contribute to an oral care program.

摘要

在之前的一项研究中,我们证明,对于一组积极性很高的护士,使用含有锌盐和三氯生的牙膏可以维持牙龈健康。我们现在研究了这种实验性牙膏对一组积极性较低的男性的效果。103名男学生接受了口腔卫生指导(OHI),并对他们的牙齿进行了专业清洁。对于每个个体,指导和清洁都在一个15分钟的时间段内完成。根据研究前的菌斑水平和牙龈出血情况,形成了两个平衡的组。一组使用实验性牙膏12个月,另一组使用对照牙膏。在6个月后和12个月后评估结果。由于接受了口腔卫生指导,在研究前阶段结束时,菌斑和牙龈出血减少。对照组即使在6个月内也未能维持这种改善。相比之下,试验组在整个12个月内菌斑水平显著降低,牙龈健康水平更高。在研究结束6个月后对现有参与者进行重新评估发现,两组的牙龈健康状况都恢复到了研究前的状态。停止使用实验性牙膏后试验组中观察到的较低牙龈健康水平进一步支持了这一结论,即这种牙膏有助于口腔护理计划。

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