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一项关于含柠檬酸锌和三氯生的牙膏对牙菌斑、牙龈健康和牙结石影响的六个月研究。

Six-month study of the effect of a dentifrice containing zinc citrate and triclosan on plaque, gingival health, and calculus.

作者信息

Svatun B, Saxton C A, Rölla G

机构信息

Department of Pedodontics, Faculty of Dentistry, University of Oslo, Norway.

出版信息

Scand J Dent Res. 1990 Aug;98(4):301-4. doi: 10.1111/j.1600-0722.1990.tb00976.x.

Abstract

In two previous studies gingival health was maintained for at least 12 months by a dentifrice containing zinc citrate and triclosan. The aims of the present study were to determine if a zinc/triclosan dentifrice would stabilize gingival health if a lower concentration of zinc was used and to investigate its effect on the formation of calculus. 101 men and women were given oral hygiene instruction and their teeth were professionally cleaned. Two balanced groups were then formed, based on the prestudy levels of gingival bleeding and calculus. One group used the zinc/triclosan dentifrice for 6 months, while the other used a control. Results were assessed after 3 months and 6 months. Following the oral hygiene instruction, plaque and gingival bleeding were assessed at the end of the 4-wk period preceding the experimental phase, and both had been reduced. This improvement was not maintained by the control group, whereas the test group exhibited significantly lower plaque levels and a higher standard of gingival health throughout the 6 months. After 3 months, levels of calculus in the control group had returned to prestudy levels. At both the 3- and 6-month assessments, significantly less calculus was observed in the test group. The improved plaque control, stabilized gingival health, and reduced calculus formation support the conclusion that a dentifrice containing 0.5% zinc citrate and 0.2% triclosan can contribute to oral care.

摘要

在之前的两项研究中,含柠檬酸锌和三氯生的牙膏可使牙龈健康维持至少12个月。本研究的目的是确定如果使用较低浓度的锌,含锌/三氯生的牙膏是否能稳定牙龈健康,并研究其对牙石形成的影响。101名男性和女性接受了口腔卫生指导,他们的牙齿也进行了专业清洁。然后根据牙龈出血和牙石的研究前水平形成两个平衡组。一组使用含锌/三氯生的牙膏6个月,另一组使用对照牙膏。在3个月和6个月后评估结果。在接受口腔卫生指导后,在实验阶段前4周结束时评估牙菌斑和牙龈出血情况,两者均有所减少。对照组未维持这种改善,而试验组在整个6个月期间牙菌斑水平显著降低,牙龈健康水平更高。3个月后,对照组的牙石水平恢复到研究前水平。在3个月和6个月的评估中,试验组观察到的牙石明显较少。牙菌斑控制的改善、牙龈健康的稳定以及牙石形成的减少支持了这样的结论,即含0.5%柠檬酸锌和0.2%三氯生的牙膏有助于口腔护理。

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