Svatun B, Saxton C A, Rölla G, van der Ouderaa F
Unilever Research, Port Sunlight Laboratory, Bebington, Wirral, England.
J Clin Periodontol. 1989 Feb;16(2):75-80. doi: 10.1111/j.1600-051x.1989.tb01617.x.
An experimental dentifrice containing zinc citrate and Triclosan was used by student nurses for 12 months without supervision, while a corresponding group used a control dentifrice. Dental flossing was not permitted during the first 6 months. Gingival health achieved in a pre-experimental period, during which oral hygiene instruction was given, was maintained by users of the experimental dentifrice for 12 months but not by users of the control dentifrice. About 1/3 of the control group used floss daily during the 2nd 6 months and significantly improved their gingival health to a level comparable to that of the experimental group. Flossing brought no extra benefit for the latter group. In the control group, approximal regions were less healthy than buccal or lingual sites. The gingival health of these sites improved significantly with daily flossing. The experimental dentifrice maintained gingival health in all sites irrespective of the use of floss. The study has confirmed that oral health can be maintained by the use of the experimental dentifrice for at least 12 months in a habitual toothbrushing regime, and that the dentifrice would be as effective and simpler than relying on the combination of brushing and regular flossing.
学生护士在无监督的情况下使用含柠檬酸锌和三氯生的实验性牙膏12个月,而另一组使用对照牙膏。在最初6个月内不允许使用牙线。在实验前期接受过口腔卫生指导后达到的牙龈健康状况,使用实验性牙膏的人维持了12个月,而使用对照牙膏的人则未维持。在第二个6个月期间,约1/3的对照组每天使用牙线,其牙龈健康状况显著改善,达到了与实验组相当的水平。牙线对后一组没有带来额外益处。在对照组中,邻面区域不如颊侧或舌侧部位健康。每天使用牙线后,这些部位的牙龈健康状况显著改善。无论是否使用牙线,实验性牙膏都能维持所有部位的牙龈健康。该研究证实,在日常刷牙方案中,使用实验性牙膏至少12个月可维持口腔健康,并且该牙膏与依靠刷牙和定期使用牙线相结合一样有效且更简便。