Suppr超能文献

急诊科老年患者出院后90天死亡率的预测:一项回顾性随访研究。

Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study.

作者信息

Hofman Susanna E, Lucke Jacinta A, Heim Noor, de Gelder Jelle, Fogteloo Anne J, Heringhaus Christian, de Groot Bas, de Craen Anton J M, Blauw Gerard Jan, Mooijaart Simon P

机构信息

Department of Gerontology and Geriatrics, Leiden University Medical Center, PO Box 9600, Leiden, 2300 RC, The Netherlands.

Department of Emergency Medicine, Leiden University Medical Center, PO Box 9600, Leiden, 2300 RC, The Netherlands.

出版信息

BMC Emerg Med. 2016 Jul 13;16(1):26. doi: 10.1186/s12873-016-0090-5.

Abstract

BACKGROUND

Older people frequently attend the emergency department (ED) and have a high risk of poor outcome as compared to their younger counterparts. Our aim was to study routinely collected clinical parameters as predictors of 90-day mortality in older patients attending our ED.

METHODS

We conducted a retrospective follow-up study at the Leiden University Medical Center (The Netherlands) among patients aged 70 years or older attending the ED in 2012. Predictors were age, gender, time and way of arrival, presenting complaint, consulting medical specialty, vital signs, pain score and laboratory testing. Cox regression analyses were performed to analyse the association between these predictors and 90-day mortality.

RESULTS

Three thousand two hundred one unique patients were eligible for inclusion. Ninety-day mortality was 10.5 % for the total group. Independent predictors of mortality were age (hazard ratio [HR] 1.06, 95 % confidence interval [95 % CI] 1.04-1.08), referral from another hospital (HR 2.74, 95 % CI 1.22-6.11), allocation to a non-surgical specialty (HR: 1.55, 95 % CI 1.13-2.14), increased respiration rate (HR up to 2.21, 95 % CI 1.25-3.92), low oxygen saturation (HR up to 1.96, 95 % CI 1.19-3.23), hypothermia (HR 2.27, 95 % CI 1.28-4.01), fever (HR 0.43, 95 % CI 0.24-0.75), high pain score (HR 1.55, 95 % CI 1.03-2.32) and the indication to perform laboratory testing (HR 3.44, 95 % CI 2.13-5.56).

CONCLUSIONS

Routinely collected parameters at the ED can predict 90-day mortality in older patients presenting to the ED. This study forms the first step towards creating a new and simple screening tool to predict and improve health outcome in acutely presenting older patients.

摘要

背景

与年轻患者相比,老年人经常前往急诊科就诊,且预后不良风险较高。我们的目的是研究常规收集的临床参数,以预测在我院急诊科就诊的老年患者90天死亡率。

方法

我们在荷兰莱顿大学医学中心对2012年70岁及以上在急诊科就诊的患者进行了一项回顾性随访研究。预测因素包括年龄、性别、到达时间和方式、主诉、会诊医学专科、生命体征、疼痛评分和实验室检查。采用Cox回归分析来分析这些预测因素与90天死亡率之间的关联。

结果

共有3201例患者符合纳入标准。全组90天死亡率为10.5%。死亡率的独立预测因素包括年龄(风险比[HR]1.06,95%置信区间[95%CI]1.04 - 1.08)、从其他医院转诊(HR 2.74,95%CI 1.22 - 6.11)、分配到非外科专科(HR: 1.55,95%CI 1.13 - 2.14)、呼吸频率增加(HR最高达2.21,95%CI 1.25 - 3.92)、低氧饱和度(HR最高达1.96,95%CI 1.19 - 3.23)、体温过低(HR 2.27,95%CI 1.28 - 4.01)、发热(HR 0.43,95%CI 0.24 - 0.75)、高疼痛评分(HR 1.55,95%CI 1.03 - 2.32)以及进行实验室检查的指征(HR 3.44,95%CI 2.13 - 5.56)。

结论

急诊科常规收集的参数可预测在急诊科就诊的老年患者的90天死亡率。本研究朝着创建一种新的简易筛查工具迈出了第一步,该工具可预测并改善急性就诊老年患者的健康结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d14/4944462/4e0012e7c9b6/12873_2016_90_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验