Sun Ming-Fang, Jiang Mi-Zu
Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2016 Jul;18(7):666-70. doi: 10.7499/j.issn.1008-8830.2016.07.019.
Gastroesophageal reflux (GER) and cow's milk allergy (CMA) are common disorders in infants. In recent years, more and more research has investigated the relationship between these two diseases. Some studies reported that about half of the cases of GER in infants younger than 1 year may be an association with CMA. Therefore, overall understanding the role of CMA on the pathogenesis of GER has a great importance on improving clinical level of diagnosis and therapy. This review article tried to elaborate advances in research on the relationship between CMA and GER in infants, including epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment.
胃食管反流(GER)和牛奶蛋白过敏(CMA)是婴儿常见的疾病。近年来,越来越多的研究探讨了这两种疾病之间的关系。一些研究报告称,1岁以下婴儿中约一半的GER病例可能与CMA有关。因此,全面了解CMA在GER发病机制中的作用对于提高临床诊断和治疗水平具有重要意义。这篇综述文章试图阐述婴儿CMA与GER关系的研究进展,包括流行病学、发病机制、临床表现、诊断和治疗。