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[婴儿牛奶蛋白过敏与胃食管反流关系的研究进展]

[Research advances in the relationship between cow's milk allergy and gastroesoph-ageal reflux in infants].

作者信息

Sun Ming-Fang, Jiang Mi-Zu

机构信息

Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2016 Jul;18(7):666-70. doi: 10.7499/j.issn.1008-8830.2016.07.019.

Abstract

Gastroesophageal reflux (GER) and cow's milk allergy (CMA) are common disorders in infants. In recent years, more and more research has investigated the relationship between these two diseases. Some studies reported that about half of the cases of GER in infants younger than 1 year may be an association with CMA. Therefore, overall understanding the role of CMA on the pathogenesis of GER has a great importance on improving clinical level of diagnosis and therapy. This review article tried to elaborate advances in research on the relationship between CMA and GER in infants, including epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment.

摘要

胃食管反流(GER)和牛奶蛋白过敏(CMA)是婴儿常见的疾病。近年来,越来越多的研究探讨了这两种疾病之间的关系。一些研究报告称,1岁以下婴儿中约一半的GER病例可能与CMA有关。因此,全面了解CMA在GER发病机制中的作用对于提高临床诊断和治疗水平具有重要意义。这篇综述文章试图阐述婴儿CMA与GER关系的研究进展,包括流行病学、发病机制、临床表现、诊断和治疗。

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Milk-induced reflux in infants less than one year of age.一岁以下婴儿的牛奶诱发反流
J Pediatr Gastroenterol Nutr. 2000;30 Suppl:S36-44. doi: 10.1097/00005176-200001001-00006.
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Vomiting and gastric motility in infants with cow's milk allergy.牛奶过敏婴儿的呕吐与胃动力
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本文引用的文献

1
Cow's milk allergy in children and adults.儿童和成人的牛奶过敏
Chem Immunol Allergy. 2015;101:114-23. doi: 10.1159/000375415. Epub 2015 May 21.
2
Non-IgE-mediated gastrointestinal food allergy.非 IgE 介导的胃肠道食物过敏。
J Allergy Clin Immunol. 2015 May;135(5):1114-24. doi: 10.1016/j.jaci.2015.03.025.
5
Diagnosis and treatment of gastroesophageal reflux disease.胃食管反流病的诊断与治疗
World J Gastrointest Pharmacol Ther. 2014 Aug 6;5(3):105-12. doi: 10.4292/wjgpt.v5.i3.105.
7
Treatment of Cow's Milk Protein Allergy.牛奶蛋白过敏的治疗
Pediatr Gastroenterol Hepatol Nutr. 2014 Mar;17(1):1-5. doi: 10.5223/pghn.2014.17.1.1. Epub 2014 Mar 31.
8
Safety of soya-based infant formulas in children.婴儿配方豆基食品的安全性。
Br J Nutr. 2014 Apr 28;111(8):1340-60. doi: 10.1017/S0007114513003942. Epub 2014 Feb 10.
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Gastro-esophageal reflux disease in healthy older children and adolescents.健康大龄儿童及青少年的胃食管反流病
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