Lin Xiaochen, Alvim Sheila M, Simoes Eduardo J, Bensenor Isabela M, Barreto Sandhi M, Schmidt Maria I, Ribeiro Antonio L, Pitanga Francisco, Almeida Maria Conceição C, Liu Simin, Lotufo Paulo A
Department of Epidemiology, School of Public Health, Brown University, Providence, RI.
Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, Brazil.
J Am Heart Assoc. 2016 Jun 13;5(6):e003337. doi: 10.1161/JAHA.116.003337.
Although increasing effort has been devoted to the promotion of a healthy lifestyle such as leisure time physical activity for cardio-metabolic health, specific evidence supporting health policy remains sparse, particularly in those ethnically diverse populations where cardio-metabolic diseases are reaching epidemic proportion and yet are grossly understudied.
We conducted a cross-sectional analysis of the baseline data from 10 585 participants aged 35 to 74 free of cardiovascular diseases in the Brazilian Longitudinal Study of Adult Health. Leisure time physical activity status was defined by the American Heart Association and the World Health Organization recommendations (≥150 min/week moderate activities or 75 min/week vigorous activities). In total, 1183 (21%) women and 1387 (29%) men were active. After accounting for covariates, the favorable effects of leisure time physical activity on cardio-metabolic parameters were evident. Specifically, the average blood pressure, heart rate, and Framingham Risk Score for cardiovascular diseases of the active were significantly lower within each sex. The ORs comparing the active versus the inactive women were 0.78 (95% CI: 0.66-0.92) for hypertension and 0.78 (95% CI: 0.65-0.93) for cardiovascular diseases in 10 years. Among men, the ORs were 0.75 (95% CI: 0.65-0.87) for hypertension and 0.73 (95% CI: 0.61-0.87) for diabetes. The 10-year risk of cardiovascular diseases was significantly lower among the active men with a 33% reduction (OR=0.67, 95% CI: 0.57-0.78).
We observed beneficial effects of leisure time physical activity on cardio-metabolic health in this large Brazilian population that are consistent with studies in North America and Europe.
尽管人们越来越致力于推广健康的生活方式,如进行休闲体育活动以促进心血管代谢健康,但支持健康政策的具体证据仍然稀少,尤其是在那些心血管代谢疾病已达到流行程度但却严重缺乏研究的种族多样化人群中。
我们对巴西成人健康纵向研究中10585名年龄在35至74岁、无心血管疾病的参与者的基线数据进行了横断面分析。休闲体育活动状况根据美国心脏协会和世界卫生组织的建议来定义(每周至少150分钟的中等强度活动或75分钟的高强度活动)。共有1183名(21%)女性和1387名(29%)男性为活跃人群。在考虑了协变量后,休闲体育活动对心血管代谢参数的有益影响是明显的。具体而言,在每个性别中,活跃人群的平均血压、心率和心血管疾病的弗雷明汉风险评分显著更低。在10年中,活跃女性与不活跃女性相比,患高血压的比值比(OR)为0.78(95%置信区间:0.66 - 0.92),患心血管疾病的OR为0.78(95%置信区间:0.65 - 0.93)。在男性中,患高血压的OR为0.75(95%置信区间:0.65 - 0.87),患糖尿病的OR为0.73(95%置信区间:0.61 - 0.87)。活跃男性患心血管疾病的10年风险显著更低,降低了33%(OR = 0.67,95%置信区间:0.57 - 0.78)。
我们在这个庞大的巴西人群中观察到休闲体育活动对心血管代谢健康有有益影响,这与北美和欧洲的研究结果一致。