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解析微生物群落中的分子相互作用。

Decoding molecular interactions in microbial communities.

作者信息

Abreu Nicole A, Taga Michiko E

机构信息

Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720-3102, USA.

Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720-3102, USA

出版信息

FEMS Microbiol Rev. 2016 Sep;40(5):648-63. doi: 10.1093/femsre/fuw019. Epub 2016 Jul 13.

DOI:10.1093/femsre/fuw019
PMID:27417261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5007284/
Abstract

Microbial communities govern numerous fundamental processes on earth. Discovering and tracking molecular interactions among microbes is critical for understanding how single species and complex communities impact their associated host or natural environment. While recent technological developments in DNA sequencing and functional imaging have led to new and deeper levels of understanding, we are limited now by our inability to predict and interpret the intricate relationships and interspecies dependencies within these communities. In this review, we highlight the multifaceted approaches investigators have taken within their areas of research to decode interspecies molecular interactions that occur between microbes. Understanding these principles can give us greater insight into ecological interactions in natural environments and within synthetic consortia.

摘要

微生物群落掌控着地球上众多的基本过程。发现并追踪微生物之间的分子相互作用对于理解单个物种和复杂群落如何影响其相关宿主或自然环境至关重要。尽管DNA测序和功能成像方面的最新技术发展带来了新的、更深入的理解层面,但我们目前仍受到限制,因为无法预测和解释这些群落中复杂的关系和种间依赖性。在这篇综述中,我们重点介绍了研究人员在其研究领域内采用的多方面方法,以解码微生物之间发生的种间分子相互作用。理解这些原理可以让我们更深入地了解自然环境和合成菌群中的生态相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1033/5007284/46edb2b3c63b/fuw019fig1g.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1033/5007284/46edb2b3c63b/fuw019fig1g.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1033/5007284/46edb2b3c63b/fuw019fig1g.jpg

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