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从诊断到管理的牛奶蛋白过敏:全科医生和家长截然不同的历程

Cow's Milk Protein Allergy from Diagnosis to Management: A Very Different Journey for General Practitioners and Parents.

作者信息

Lozinsky Adriana C, Meyer Rosan, Anagnostou Katherine, Dziubak Robert, Reeve Kate, Godwin Heather, Fox Adam T, Shah Neil

机构信息

Department of Paediatric Gastroenterology, Great Ormond Street Children's Hospital, London WC1N 3JH, UK.

Department of Paediatric Allergy, Guy's and St Thomas' Hospitals NHS Foundation Trust, Westminster Bridge Road, London SE1 7EH, UK.

出版信息

Children (Basel). 2015 Jul 21;2(3):317-29. doi: 10.3390/children2030317.

DOI:10.3390/children2030317
PMID:27417366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4928770/
Abstract

Cow's milk protein allergy (CMPA) is the most common food allergy in infants and can affect a family's quality of life. The purpose of this paper is to evaluate the knowledge and experience of general practitioners (GPs) in terms of CMPA diagnosis and management and to explore the views of parents on the current diagnostic process. Two surveys were conducted in June 2014, which collected data from GPs and parents of infants diagnosed with CMPA in the United Kingdom. The questionnaires included quantitative and qualitative questions, which measured self-reported knowledge, management and perceived treatment progression, and the educational needs of GPs. We also explored parents' experiences of local healthcare support in relation to CMPA. A total of 403 GPs and 300 parents completed the surveys. The main symptoms of CMPA and diagnosis period differed between GPs and parents. Other key points include different perceptions on symptom presentation and improvement, lack of awareness from GPs about current guidelines, and the significant burden on both families and GPs. This is the first study attempting to establish GP and parental experience in diagnosing CMPA. It is notable that the difference can be improved through training, appropriate diagnostic tools and improved communication between physicians and parents.

摘要

牛奶蛋白过敏(CMPA)是婴儿中最常见的食物过敏,会影响家庭生活质量。本文旨在评估全科医生(GPs)在CMPA诊断和管理方面的知识与经验,并探讨家长对当前诊断过程的看法。2014年6月进行了两项调查,收集了来自英国被诊断为CMPA的婴儿的全科医生和家长的数据。问卷包括定量和定性问题,测量自我报告的知识、管理和感知的治疗进展,以及全科医生的教育需求。我们还探讨了家长在CMPA方面获得当地医疗支持的经历。共有403名全科医生和300名家长完成了调查。全科医生和家长对CMPA的主要症状和诊断时期看法不同。其他关键点包括对症状表现和改善的不同认知、全科医生对当前指南缺乏认识,以及给家庭和全科医生带来的巨大负担。这是第一项试图确立全科医生和家长在诊断CMPA方面经验的研究。值得注意的是,通过培训、合适的诊断工具以及改善医生与家长之间的沟通,这种差异是可以改善的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a916/4928770/83078f385418/children-02-00317-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a916/4928770/8395fa5cd122/children-02-00317-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a916/4928770/b5351d44ebc4/children-02-00317-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a916/4928770/83078f385418/children-02-00317-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a916/4928770/8395fa5cd122/children-02-00317-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a916/4928770/b5351d44ebc4/children-02-00317-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a916/4928770/83078f385418/children-02-00317-g003.jpg

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本文引用的文献

1
Non-IgE-mediated gastrointestinal food allergy.非 IgE 介导的胃肠道食物过敏。
J Allergy Clin Immunol. 2015 May;135(5):1114-24. doi: 10.1016/j.jaci.2015.03.025.
2
Food allergy competencies of dietitians in the United Kingdom, Australia and United States of America.英国、澳大利亚和美国营养师的食物过敏专业能力。
Clin Transl Allergy. 2014 Nov 14;4:37. doi: 10.1186/2045-7022-4-37. eCollection 2014.
3
The development of a standardised diet history tool to support the diagnosis of food allergy.开发标准化饮食史工具以支持食物过敏诊断。
“你随过敏一同成长”:一项关于家庭在幼儿期食物过敏风险或诊断经历的扎根理论研究
BMJ Open. 2024 Dec 12;14(12):e089751. doi: 10.1136/bmjopen-2024-089751.
4
The evolution of Cow's Milk-related Symptom Score (CoMiSS™) in presumed healthy infants.疑似健康婴儿的牛奶相关症状评分(CoMiSS)的演变。
Eur J Pediatr. 2024 Oct;183(10):4329-4335. doi: 10.1007/s00431-024-05693-2. Epub 2024 Jul 30.
5
Impact of the 2022 national formula shortage on clinical decision-making of healthcare providers in switching amino acid formulas for infants with cow's milk protein allergy: a survey-based study.2022年全国配方奶粉短缺对医疗服务提供者为牛奶蛋白过敏婴儿更换氨基酸配方奶粉临床决策的影响:一项基于调查的研究
Front Pediatr. 2024 Mar 15;12:1328506. doi: 10.3389/fped.2024.1328506. eCollection 2024.
6
Clinician Experience with Using Hypoallergenic Formulas to Treat Infants with Suspected Cow's Milk Protein Allergy: A Secondary Analysis of a Prospective Survey Cohort.临床医生使用低敏配方奶粉治疗疑似牛奶蛋白过敏婴儿的经验:一项前瞻性调查队列的二次分析
Pediatr Gastroenterol Hepatol Nutr. 2023 Sep;26(5):277-283. doi: 10.5223/pghn.2023.26.5.277. Epub 2023 Sep 1.
7
World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guideline update - VII - Milk elimination and reintroduction in the diagnostic process of cow's milk allergy.世界过敏组织(WAO)牛奶过敏诊断与治疗原理指南(DRACMA)更新——VII——牛奶过敏诊断过程中的牛奶回避与重新引入
World Allergy Organ J. 2023 Jul 24;16(7):100785. doi: 10.1016/j.waojou.2023.100785. eCollection 2023 Jul.
8
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Pediatr Gastroenterol Hepatol Nutr. 2023 Jan;26(1):43-49. doi: 10.5223/pghn.2023.26.1.43. Epub 2023 Jan 10.
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World Allergy Organ J. 2022 Nov 17;15(12):100717. doi: 10.1016/j.waojou.2022.100717. eCollection 2022 Dec.
Clin Transl Allergy. 2015 Feb 19;5:7. doi: 10.1186/s13601-015-0050-2. eCollection 2015.
4
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7
Feeding difficulties in children with food protein-induced gastrointestinal allergies.食物蛋白诱导的胃肠道过敏儿童的喂养困难
J Gastroenterol Hepatol. 2014 Oct;29(10):1764-9. doi: 10.1111/jgh.12593.
8
Extraintestinal manifestations in children with gastrointestinal food allergy.患有胃肠道食物过敏的儿童的肠外表现
J Pediatr Gastroenterol Nutr. 2014 Aug;59(2):210-4. doi: 10.1097/MPG.0000000000000391.
9
European pediatricians' approach to children with GER symptoms: survey of the implementation of 2009 NASPGHAN-ESPGHAN guidelines.欧洲儿科医生对有胃食管反流症状儿童的处理方式:2009年NASPGHAN-ESPGHAN指南实施情况调查
J Pediatr Gastroenterol Nutr. 2014 Apr;58(4):505-9. doi: 10.1097/MPG.0b013e3182a69912.
10
BSACI guideline for the diagnosis and management of cow's milk allergy.英国变态反应与临床免疫学会牛奶过敏诊断和管理指南。
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