人工甜味饮料与儿童肥胖：争议仍在继续。
Artificial Sweetened Beverages and Pediatric Obesity: The Controversy Continues.
作者信息
Freswick Peter N
机构信息
Department of Pediatric Gastroenterology, Vanderbilt University, Nashville, TN 37232, USA.
出版信息
Children (Basel). 2014 May 28;1(1):31-9. doi: 10.3390/children1010031.
The pediatric obesity epidemic has gathered public and political interest recently. People often choose "diet" or artificial sweetened beverages (ASB) to combat this epidemic, but the obesity incidence continues to rise. First, I review the pediatric studies on the effect of ASB consumption with subsequent food intake. Next, I present pediatric studies of chronic ASB consumption and weight change. Some epidemiologic pediatric studies have supported an association between artificial sweetener use and increased BMI but cannot prove causation. Randomized control trials have provided some evidence of weight loss with ASB ingestion among children, but study limitations may minimize these conclusions. Finally, I summarize the possible mechanisms that may drive potential effects of artificial sweeteners.
儿童肥胖流行问题近来已引起公众和政界的关注。人们常常选择“节食”或人工甜味饮料（ASB）来应对这一流行问题，但肥胖发病率仍在持续上升。首先，我回顾一下关于饮用ASB对后续食物摄入量影响的儿童研究。接下来，我介绍一下长期饮用ASB与体重变化的儿童研究。一些儿科流行病学研究支持人工甜味剂的使用与体重指数增加之间存在关联，但无法证明其因果关系。随机对照试验提供了一些儿童摄入ASB后体重减轻的证据，但研究的局限性可能会削弱这些结论。最后，我总结了可能导致人工甜味剂产生潜在影响的机制。
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