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低出生体重儿中由“新生儿”头状葡萄球菌引起的晚发性败血症:一种新的病症?

Late-onset sepsis due to Staphylococcus capitis 'neonatalis' in low-birthweight infants: a new entity?

作者信息

Ben Said M, Hays S, Bonfils M, Jourdes E, Rasigade J-P, Laurent F, Picaud J-C

机构信息

Neonatology, University Hospital Croix Rousse, Hospices Civils de Lyon, Lyon, France; Faculty of Medicine of Tunis, University of Tunis El-Manar, Tunis, Tunisia.

Neonatology, University Hospital Croix Rousse, Hospices Civils de Lyon, Lyon, France; Rhone-Alpes Human Nutrition Research Centre, Pierre Bénite, France.

出版信息

J Hosp Infect. 2016 Sep;94(1):95-8. doi: 10.1016/j.jhin.2016.06.008. Epub 2016 Jun 17.

DOI:10.1016/j.jhin.2016.06.008
PMID:27424947
Abstract

During hospitalization, sepsis occurs in one of every five very-low-birthweight infants. The emergence of Staphylococcus capitis (SC)-related sepsis in preterm infants was observed recently. This study aimed to evaluate the clinical severity of SC-related sepsis in preterm infants. Of the 105 infants who presented with sepsis related to coagulase-negative staphylococci, 74 were SC. Severe morbidity was more common in the SC group (55.4%) than in the non-SC coagulase-negative staphylococci group (32.0%) (P=0.03). Multi-variate analysis identified SC-related sepsis as an independent risk factor for severe morbidity.

摘要

在住院期间,每五名极低出生体重儿中就有一名会发生败血症。近期观察到早产儿中出现了与头状葡萄球菌(SC)相关的败血症。本研究旨在评估早产儿中与SC相关的败血症的临床严重程度。在105例出现与凝固酶阴性葡萄球菌相关败血症的婴儿中,74例为SC。SC组严重发病情况(55.4%)比非SC凝固酶阴性葡萄球菌组(32.0%)更常见(P=0.03)。多变量分析确定与SC相关的败血症是严重发病的独立危险因素。

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