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Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.成人及儿童B细胞急性淋巴细胞白血病的基因组分析
EBioMedicine. 2016 Jun;8:173-183. doi: 10.1016/j.ebiom.2016.04.038. Epub 2016 May 13.
2
Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults.青少年和年轻成人 B 细胞急性淋巴细胞白血病中的复发性 DUX4 融合。
Nat Genet. 2016 May;48(5):569-74. doi: 10.1038/ng.3535. Epub 2016 Mar 28.
3
A novel recurrent EP300-ZNF384 gene fusion in B-cell precursor acute lymphoblastic leukemia.B细胞前体急性淋巴细胞白血病中一种新的复发性EP300-ZNF384基因融合
Leukemia. 2015 Dec;29(12):2445-8. doi: 10.1038/leu.2015.111. Epub 2015 May 6.
4
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.BCL6与前B细胞受体信号传导之间的自我强化反馈激活定义了急性淋巴细胞白血病的一种独特亚型。
Cancer Cell. 2015 Mar 9;27(3):409-25. doi: 10.1016/j.ccell.2015.02.003.
5
Beyond Philadelphia: 'Ph-like' B cell precursor acute lymphoblastic leukemias - diagnostic challenges and therapeutic promises.超越费城：“费城样”B细胞前体急性淋巴细胞白血病——诊断挑战与治疗前景
Curr Opin Hematol. 2014 Jul;21(4):289-96. doi: 10.1097/MOH.0000000000000050.
6
An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions.基因内 ERG 缺失是一种 B 细胞前体急性淋巴细胞白血病的致癌亚型标志物，尽管 IKZF1 缺失频繁，但预后良好。
Leukemia. 2014 Jan;28(1):70-7. doi: 10.1038/leu.2013.277. Epub 2013 Sep 25.
7
Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.高危儿童急性淋巴细胞白血病中常发生关键通路突变：来自儿童肿瘤协作组的报告。
Blood. 2011 Sep 15;118(11):3080-7. doi: 10.1182/blood-2011-03-341412. Epub 2011 Jun 16.
8
Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome.基于基因表达谱鉴定儿童高危 B 前体细胞急性淋巴细胞白血病中的新型聚类群：与全基因组 DNA 拷贝数改变、临床特征和预后的相关性。
Blood. 2010 Dec 2;116(23):4874-84. doi: 10.1182/blood-2009-08-239681. Epub 2010 Aug 10.
9
DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.DUX4是面肩肱型肌营养不良症的一个候选基因，编码PITX1的转录激活因子。
Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18157-62. doi: 10.1073/pnas.0708659104. Epub 2007 Nov 5.
10
Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemia.急性淋巴细胞白血病中由变异型t(1;19)(q23;p13.3)产生的MEF2D/DAZAP1和DAZAP1/MEF2D融合蛋白的克隆及功能特性分析
Leukemia. 2005 May;19(5):806-13. doi: 10.1038/sj.leu.2403684.

Deciphering "B-others": Novel fusion genes driving B-cell acute lymphoblastic leukemia.

作者信息

Izraeli Shai

机构信息

Department of Pediatric Hematology and Oncology, Leukemia Research Section, Edmond and Lily Children's Hospital, Sheba Medical Center, Ramat Gan 52621, Israel; Department of Molecular Human Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

EBioMedicine. 2016 Jun;8:8-9. doi: 10.1016/j.ebiom.2016.06.001. Epub 2016 Jun 2.

DOI:10.1016/j.ebiom.2016.06.001
PMID:27428404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4919499/
Abstract
摘要