Potapenko A Ia, Bezdetnaia L N, Akhtiamov S N, Perkhova O Iu, Sukhorukov V L
Biofizika. 1989 Mar-Apr;34(2):195-8.
Antioxidants butylated hydroxytoluene++ (ionol) and 2,2,5,7,8-pentamethyl-chromanol-6-(alpha-T-0) were shown to inhibit hemolysis induced by the ethanolic solution of photooxidized psoralen (POP). This inhibition appeared to be the same whether antioxidants were present during irradiation or were added immediately after photooxidation. Therefore antioxidants do not influence POP formation, but inhibit the interaction of POP degradation products in water with biomolecules. Possibility of POP participation in phototoxic effects of furocoumarins is discussed.
抗氧化剂丁基化羟基甲苯（ionol）和2,2,5,7,8 - 五甲基色满醇 - 6（α - T - 0）被证明可抑制光氧化补骨脂素（POP）乙醇溶液诱导的溶血。无论抗氧化剂是在照射期间存在还是在光氧化后立即添加，这种抑制作用似乎都是相同的。因此，抗氧化剂不会影响POP的形成，但会抑制水中POP降解产物与生物分子的相互作用。文中讨论了POP参与呋喃香豆素光毒性作用的可能性。
