Malo Annie, Cluzel Caroline, Labrecque Olivia, Beauchamp Guy, Lavoie Jean-Pierre, Leclere Mathilde
Department of Clinical Sciences (Malo, Lavoie, Leclere), Department of Pathology and Microbiology (Cluzel), Veterinary Biomedicine Department (Beauchamp), Faculty of Veterinary Medicine, Université de Montréal, 3200 Sicotte, St. Hyacinthe, Quebec J2S 7C6; Laboratoire d'épidémiosurveillance animale, Ministère de l'Agriculture des Pêcheries et de l'Alimentation du Québec, St. Hyacinthe, Quebec (Labrecque).
Can Vet J. 2016 Jul;57(7):747-51.
This study identified antimicrobial resistance patterns of commonly isolated bacteria at the Equine Hospital of the Université de Montréal between 2007 and 2013, and compared the results with the resistance patterns observed in tests performed in previous decades in the same hospital. A total of 396 antimicrobial susceptibility tests were analyzed by the Kirby-Bauer method during the period 2007 to 2013 and compared to 233 and 255 tests completed in 1986 to 1988 and 1996 to 1998, respectively. The most common bacteria were Streptococcus equi subsp. zooepidemicus (S. zooepidemicus) and Escherichia coli. Except for resistance of coagulase-positive staphylococci to trimethoprim-sulfamethoxazole, there was no overall increase in resistance observed between 1986 to 1988 and 2007 to 2013 for antimicrobials reported for all 3 periods. However, between 1996 to 1998 and 2007 to 2013, there was an increase in in vitro resistance to enrofloxacin for E. coli and Enterobacter spp., and to ceftiofur for Enterobacter spp. and coagulase-positive staphylococci. No increase in resistance was observed for S. zooepidemicus and no isolate was resistant to penicillin.
本研究确定了2007年至2013年蒙特利尔大学马医院常见分离细菌的抗菌耐药模式,并将结果与该医院前几十年检测中观察到的耐药模式进行了比较。2007年至2013年期间,共通过 Kirby-Bauer 方法分析了396次抗菌药敏试验,并分别与1986年至1988年及1996年至1998年完成的233次和255次试验进行比较。最常见的细菌是马链球菌兽疫亚种(兽疫链球菌)和大肠杆菌。除凝固酶阳性葡萄球菌对甲氧苄啶-磺胺甲恶唑耐药外,在所有三个时期报告的抗菌药物中,1986年至1988年与2007年至2013年之间未观察到总体耐药性增加。然而,在1996年至1998年与2007年至2013年之间,大肠杆菌和肠杆菌属对恩诺沙星的体外耐药性增加,肠杆菌属和凝固酶阳性葡萄球菌对头孢噻呋的耐药性增加。兽疫链球菌未观察到耐药性增加,且没有分离株对青霉素耐药。