Gilliam Wesley P, Craner Julia R, Morrison Eleshia J, Sperry Jeannie A
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN.
Clin J Pain. 2017 May;33(5):443-451. doi: 10.1097/AJP.0000000000000419.
Although reducing pain catastrophizing has been shown to contribute to functional improvement in patients receiving interdisciplinary pain care, little is known about how changes in the different dimensions of pain catastrophizing uniquely contribute to improvement in outcome. The study examined the unique relationship between changes in the 3 distinct factors of pain catastrophizing-helplessness, rumination, and magnification-and changes in pain outcomes.
In this nonrandomized study, 641 patients who completed treatment in a 3-week interdisciplinary pain rehabilitation program between the years 2013 and 2014 completed a battery of psychometrically validated measures of pain catastrophizing, pain severity, pain interference, mental and physical health-related quality of life, and depressive symptoms at pretreatment and posttreatment.
A series of within groups (repeated measures) mediation analyses were conducted. Change in the helplessness, rumination, and magnification subscales were entered as multiple mediators in the model. Analyses revealed that change in helplessness partially mediated improvement in all outcome variables beyond the influence of change in other variables in the model, whereas change in rumination partially mediated improvement in pain severity, interference, and depressive symptoms. Change in magnification had the least impact on outcome, partially mediating improvements in only mental health quality of life.
Results suggest that changes in the 3 dimensions of pain catastrophizing differentially mediate improvement in pain outcome. Treatment approaches that specifically target helplessness and rumination may be particularly useful in improving the outcomes of patients with refractory pain conditions enrolled in interdisciplinary pain rehabilitation program.
尽管已有研究表明,减少疼痛灾难化思维有助于接受多学科疼痛治疗的患者功能改善,但对于疼痛灾难化思维不同维度的变化如何独特地促进治疗效果改善,我们所知甚少。本研究探讨了疼痛灾难化思维的三个不同因素——无助感、沉思和放大——的变化与疼痛结局变化之间的独特关系。
在这项非随机研究中,641名于2013年至2014年间在为期3周的多学科疼痛康复项目中完成治疗的患者,在治疗前和治疗后完成了一系列经过心理测量学验证的疼痛灾难化思维、疼痛严重程度、疼痛干扰、与心理和身体健康相关的生活质量以及抑郁症状的测量。
进行了一系列组内(重复测量)中介分析。将无助感、沉思和放大子量表的变化作为多个中介因素纳入模型。分析显示,无助感的变化在模型中其他变量变化的影响之外,部分中介了所有结局变量的改善,而沉思的变化部分中介了疼痛严重程度、干扰和抑郁症状的改善。放大的变化对结局的影响最小,仅部分中介了心理健康生活质量的改善。
结果表明,疼痛灾难化思维的三个维度的变化对疼痛结局改善的中介作用各不相同。专门针对无助感和沉思的治疗方法可能对改善参加多学科疼痛康复项目的顽固性疼痛患者的结局特别有用。