Martinot A, Hue V, Leclerc F, Chenaud M
Paediatric Intensive Care Unit, Université de Lille, Hôpital Calmette, France.
Eur J Pediatr. 1989 Jun;148(7):648-9. doi: 10.1007/BF00441523.
We report the first case of Haemolytic-uraemic syndrome (HUS) associated with Streptococcus pneumoniae meningitis. This supports a common pathogenic mechanism in HUS following infections by neuraminidase-producing organisms and in pneumococcal meningitis. We recommend that HUS must be considered in cases of renal failure and/or anaemia associated with pneumococcal meningitis, and that bacterial meningitis be considered in all patients with HUS and central nervous system involvement.
我们报告了首例与肺炎链球菌脑膜炎相关的溶血尿毒综合征（HUS）病例。这支持了在由产生神经氨酸酶的生物体感染后发生的HUS以及肺炎球菌脑膜炎中存在共同致病机制的观点。我们建议，对于伴有肺炎球菌脑膜炎的肾衰竭和/或贫血病例，必须考虑到HUS的可能性；对于所有伴有中枢神经系统受累的HUS患者，均应考虑细菌性脑膜炎的可能性。
