Rayment Jonathan H, Narang Indra
Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Can Respir J. 2016;2016:4575942. doi: 10.1155/2016/4575942. Epub 2016 Feb 25.
Chronic granulomatous disease (CGD) is a rare, polygenic primary immunodeficiency. In this case report, we describe a previously healthy 13-year-old boy who presented with multifocal pulmonary aspergillosis and was subsequently diagnosed with an autosomal recessive form of chronic granulomatous disease. CGD has a variable natural history and age of presentation and should be considered when investigating a patient with recurrent or severe infections with catalase-positive organisms.
慢性肉芽肿病（CGD）是一种罕见的多基因原发性免疫缺陷病。在本病例报告中，我们描述了一名既往健康的13岁男孩，他因多灶性肺曲霉菌病就诊，随后被诊断为常染色体隐性遗传形式的慢性肉芽肿病。CGD有不同的自然病程和发病年龄，在对反复或严重感染过氧化氢酶阳性微生物的患者进行调查时应考虑到该病。
