Nishizumi M
Fukuoka Igaku Zasshi. 1989 May;80(5):240-5.
In order to examine the carcinogenicity of 2,3,4,7,8-pentachlorodibenzofuran and 1,2,3,4,7,8-hexachlorodibenzofuran, these two chemicals were subcutaneously administered to Wistar strain male rats at the dose of 80 micrograms, 40 micrograms or 4 micrograms per rat. At sacrifice in two years after the start of the experiment, tumors were observed in the subcutaneous tissue and the liver. Although the number of the rats used is small, the tumor occurrence showed some tendency to relate with the dose of the chemicals given.
为检测2,3,4,7,8 - 五氯二苯并呋喃和1,2,3,4,7,8 - 六氯二苯并呋喃的致癌性，将这两种化学物质以每只大鼠80微克、40微克或4微克的剂量皮下注射给Wistar品系雄性大鼠。在实验开始两年后处死大鼠时，在皮下组织和肝脏中观察到肿瘤。尽管所用大鼠数量较少，但肿瘤发生呈现出与所给化学物质剂量相关的某种趋势。
