一种用于具有游离还原端的碳水化合物自动聚糖组装的无痕光可裂解连接子。
A traceless photocleavable linker for the automated glycan assembly of carbohydrates with free reducing ends.
作者信息
Wilsdorf M, Schmidt D, Bartetzko M P, Dallabernardina P, Schuhmacher F, Seeberger P H, Pfrengle F
机构信息
Department of Biomolecular Systems, Max-Planck-Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.
出版信息
Chem Commun (Camb). 2016 Aug 9;52(66):10187-9. doi: 10.1039/c6cc04954k.
We report a traceless photocleavable linker for the automated glycan assembly of carbohydrates with free reducing ends. The reductive-labile functionality in the linker tolerates all commonly used reagents and protocols for automated glycan assembly, as demonstrated with the successful preparation of nine plant cell wall-related oligosaccharides, and is cleaved by hydrogenolysis.
我们报道了一种用于具有游离还原端的碳水化合物自动聚糖组装的无痕光可裂解连接子。连接子中对还原不稳定的官能团能耐受自动聚糖组装中所有常用的试剂和方案，这在成功制备九种植物细胞壁相关寡糖中得到了证明，并且该连接子可通过氢解作用裂解。
Zotero 插件