Israel Yair, Rachmiel Adi, Ziv Gil, Nagler Rafael
Department of Oral and Maxillofacial Surgery, Rambam Medical Center, Faculty of Medicine, Rappaport Family Institute for Research in the Medical Sciences, Technion - Israel Institute of Technology, Haifa, Israel.
Department of Otolaryngology Head and Neck Surgery, Rambam Medical Center, Faculty of Medicine, Rappaport Family Institute for Research in the Medical Sciences, Technion - Israel Institute of Technology, Haifa, Israel.
Anticancer Res. 2016 Aug;36(8):4151-4.
To examine the demographic, ethnic, and clinical characteristics of salivary benign and malignant tumors for better etiological understanding.
We examined medical records of 287 primary salivary gland tumor patients.
Overall, 216 tumors were benign and 71 malignant. The mean age at diagnosis was 56.4 years for those with malignant tumors and 48.5 years for those with benign, a highly significant difference (p=0.001). Females had 45% of malignant tumors and 59% of benign, a significant difference (p=0.037). Ethnic origin, alcohol consumption and cigarette smoking rates were not significantly different (p>0.05) between groups. A total of 87% of benign and 55% of malignant tumors were in the parotid glands, a highly significant predilection (p<0.0001), sublocated mostly in the superfacial lobe; 36.6% of malignant tumors and 4.7% of benign (p<0.0001) were in the minor salivary glands, mostly in the hard palate.
Baseline clinical, demographic and locational aspects of benign and malignant tumors are substantiated.
研究唾液腺良恶性肿瘤的人口统计学、种族及临床特征，以更好地理解其病因。
我们检查了287例原发性唾液腺肿瘤患者的病历。
总体而言，216例肿瘤为良性，71例为恶性。恶性肿瘤患者的诊断平均年龄为56.4岁，良性肿瘤患者为48.5岁，差异具有高度显著性（p = 0.001）。女性患恶性肿瘤的比例为45%，患良性肿瘤的比例为59%，差异具有显著性（p = 0.037）。两组之间的种族、饮酒率和吸烟率无显著差异（p>0.05）。87%的良性肿瘤和55%的恶性肿瘤位于腮腺，具有高度显著的倾向性（p<0.0001），主要位于浅叶；36.6%的恶性肿瘤和4.7%的良性肿瘤（p<0.0001）位于小唾液腺，主要位于硬腭。
良恶性肿瘤的基线临床、人口统计学及位置特征得到证实。
