Praidou Anna, Harris Martin, Niakas Dimitrios, Labiris Georgios
Dept. of Ophthalmology, Royal Free London NHS Foundation Trust, London, United Kingdom; Faculty of Social Sciences, Hellenic Open University, Patra, Greece.
Dept. of Ophthalmology, Royal Free London NHS Foundation Trust, London, United Kingdom.
J Diabetes Complications. 2017 Feb;31(2):456-461. doi: 10.1016/j.jdiacomp.2016.06.027. Epub 2016 Jun 29.
The lack of physical activity, along with obesity, smoking, hypertension and hyperglycaemia are considered as risk factors for the occurrence of diseases such as diabetes. Primary objective of the study was to investigate potential correlation between physical activity and diabetic retinopathy.
Three hundred and twenty patients were included in the study: 240 patients with diabetes type 2 (80 patients with mild to moderate non-proliferative diabetic retinopathy, 80 patients with severe to very severe non-proliferative diabetic retinopathy and 80 ones with proliferative diabetic retinopathy) were compared with 80 non-diabetic patients (control group). Physical activity of patients was assessed by the international physical activity questionnaire (IPAQ, 2002). HbA1c and BMI were also measured in diabetic patients. Group comparisons were attempted for levels of physical activity and sedentary behavior.
Total physical activity was decreased in patients with severe to very severe non-proliferative diabetic retinopathy and proliferative diabetic retinopathy as compared to patients with mild to moderate non-proliferative diabetic retinopathy and to the control group (p<0.05). Significant negative correlation was detected between HbA1c levels, BMI and physical activity (both p<0.05). Moreover, significant negative correlation between the severity of diabetic retinopathy and physical activity has been demonstrated (p<0.05).
Increased physical activity is associated with less severe levels of diabetic retinopathy, independent of the effects of HbA1c and BMI.
缺乏体育活动，连同肥胖、吸烟、高血压和高血糖，被视为糖尿病等疾病发生的风险因素。该研究的主要目的是调查体育活动与糖尿病视网膜病变之间的潜在相关性。
320名患者纳入研究：240名2型糖尿病患者（80名轻度至中度非增殖性糖尿病视网膜病变患者、80名重度至极重度非增殖性糖尿病视网膜病变患者和80名增殖性糖尿病视网膜病变患者）与80名非糖尿病患者（对照组）进行比较。患者的体育活动通过国际体育活动问卷（IPAQ，2002）进行评估。还对糖尿病患者测量了糖化血红蛋白（HbA1c）和体重指数（BMI）。对体育活动水平和久坐行为进行了组间比较。
与轻度至中度非增殖性糖尿病视网膜病变患者和对照组相比，重度至极重度非增殖性糖尿病视网膜病变患者和增殖性糖尿病视网膜病变患者的总体育活动减少（p<0.05）。在糖化血红蛋白水平、体重指数和体育活动之间检测到显著的负相关（两者p<0.05）。此外，已证明糖尿病视网膜病变的严重程度与体育活动之间存在显著的负相关（p<0.05）。
增加体育活动与较轻程度的糖尿病视网膜病变相关，独立于糖化血红蛋白和体重指数的影响。
