Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing Engineering Research Center for Edible Mushroom, Key Laboratory of Urban Agriculture (North), Ministry of Agriculture, Beijing 100097, PR China; College of Life Science, Shandong Agricultural University, Taian 271018, PR China.
College of Life Science, Shandong Agricultural University, Taian 271018, PR China.
Carbohydr Polym. 2016 Oct 20;151:1227-1234. doi: 10.1016/j.carbpol.2016.06.058. Epub 2016 Jun 16.
Two polysaccharides, EIPS and AIPS were obtained by the hydrolysis of IPS from Termitomyces albuminosus, and their pharmacological effects on blood lipid profiles metabolism and oxidative stress were investigated. The results demonstrated that EIPS was superior to IPS and AIPS on reducing hepatic lipid levels and preventing oxidative stress by improving serum enzyme activities (ALT, AST, and ALP), serum lipid levels (TC, TG, HDL-C, LDL-C and VLDL-C), hepatic lipid levels (TC and TG), and antioxidant status (SOD, GSH-Px, CAT, T-AOC, MDA, and LPO). These conclusions indicated that EIPS, AIPS and IPS might be suitable for functional foods and natural drugs on preventing the high-fat emulsion-induced hyperlipidemia. In addition, the monosaccharide compositions of IPS and its hydrolyzate were also processed.
两种多糖，EIPS 和 AIPS，是通过水解从白肉齿菌中获得的 IPS 得到的，并研究了它们对血脂谱代谢和氧化应激的药理作用。结果表明，EIPS 在降低肝脂质水平和通过改善血清酶活性（ALT、AST 和 ALP）、血清脂质水平（TC、TG、HDL-C、LDL-C 和 VLDL-C）、肝脂质水平（TC 和 TG）和抗氧化状态（SOD、GSH-Px、CAT、T-AOC、MDA 和 LPO）来预防氧化应激方面优于 IPS 和 AIPS。这些结论表明，EIPS、AIPS 和 IPS 可能适合作为功能性食品和天然药物，用于预防高脂肪乳剂诱导的高脂血症。此外，IPS 及其水解产物的单糖组成也进行了处理。
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