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基于敏感电刺激提示对帕金森病的影响:一项初步研究。

Effects of Sensitive Electrical Stimulation Based Cueing in Parkinson's Disease: A Preliminary Study.

作者信息

Sijobert Benoît, Azevedo-Coste Christine, Andreu David, Verna Claudia, Geny Christian

机构信息

INRIA - LIRMM Université de Montpellier , Montpellier, France.

CHU Montpellier , Montpellier, France.

出版信息

Eur J Transl Myol. 2016 Jun 13;26(2):6018. doi: 10.4081/ejtm.2016.6018.

Abstract

This study aims to investigate the effect of a sensitive cueing on Freezing of Gait (FOG) and gait disorders in subjects suffering from Parkinson's disease (PD). 13 participants with Parkinson's disease were equipped with an electrical stimulator and a foot mounted inertial measurement unit (IMU). An IMU based algorithm triggered in real time an electrical stimulus applied on the arch of foot at heel off detection. Starting from standing, subjects were asked to walk at their preferred speed on a path comprising 5m straight, u-turn and walk around tasks. Cueing globally decreased the time to achieve the different tasks in all the subjects. In "freezer" subjects, the time to complete the entire path was reduced by 19%. FOG events occurrence was lowered by 12% compared to baseline before and after cueing. This preliminary work showed a positive global effect of an electrical stimulation based cueing on gait and FOG in PD.

摘要

本研究旨在调查敏感提示对帕金森病(PD)患者步态冻结(FOG)和步态障碍的影响。13名帕金森病患者配备了电刺激器和足部惯性测量单元(IMU)。基于IMU的算法在足跟离地检测时实时触发施加在足弓上的电刺激。从站立开始,要求受试者以他们喜欢的速度在一条包括5米直线、U形转弯和绕行任务的路径上行走。提示总体上减少了所有受试者完成不同任务的时间。在“冻结者”受试者中,完成整个路径的时间减少了19%。与提示前后的基线相比,FOG事件的发生率降低了12%。这项初步工作表明,基于电刺激的提示对PD患者的步态和FOG有积极的总体影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eec8/4942708/ce1c6bf28d31/ejtm-2016-2-6018-g001.jpg

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