Department of Haematology, Peterborough City Hospital, Peterborough, PE3 9GZ, UK.
Department of Chemistry, Loughborough University, Loughborough, LE11 3TU, UK.
Nanomedicine (Lond). 2016 Aug;11(16):2197-214. doi: 10.2217/nnm-2016-0097. Epub 2016 Aug 2.
An accurate characterization of nanomaterials used in clinical diagnosis and therapeutics is of paramount importance to realize the full potential of nanotechnology in medicine and to avoid unexpected and potentially harmful toxic effects due to these materials. A number of technical modalities are currently in use to study the physical, chemical and biological properties of nanomaterials but they all have advantages and disadvantages. In this review, we discuss the potential of a relative newcomer, tunable resistive pulse sensing, for the characterization of nanomaterials and its applications in nanodiagnostics.
在临床诊断和治疗中使用的纳米材料的准确描述对于实现纳米技术在医学中的全部潜力以及避免由于这些材料而产生的意外和潜在有害的毒性作用至关重要。目前有许多技术手段可用于研究纳米材料的物理、化学和生物学特性，但它们都有优点和缺点。在这篇综述中，我们讨论了相对较新的可调电阻脉冲感应技术在纳米材料表征及其在纳米诊断中的应用的潜力。
