Lovell Natasha, Jones Chris, Baynes Dawn, Dinning Sarah, Vinen Katie, Murtagh Fliss Em
1 Cicely Saunders Institute, Department of Palliative Care, Policy and Rehabilitation, King's College London, London, UK.
2 Imperial College London, London, UK.
Palliat Med. 2017 Mar;31(3):283-288. doi: 10.1177/0269216316655747. Epub 2016 Aug 19.
Meeting place-of-death preferences is an important measure of the quality of end-of-life care. Systematic review shows that 42% of end-stage kidney disease patients prefer home death. Little research has been undertaken on place of death.
To understand patterns of place of death in patients with end-stage kidney disease known in one UK renal unit.
A retrospective cohort study of all patients with chronic kidney disease stage 4-5, age ⩾75 and known to one UK renal unit, who died between 2006 and 2012. Patients were categorised into three management pathways: haemodialysis, conservative and pre-dialysis.
A total of 321 patients (mean age, 82.7; standard deviation, 5.21) died (61.7% male). In all, 62.9% died in hospital (95% confidence interval, 57.5%-68.1%), 21.8% died in their usual place of residence (95% confidence interval, 17.5%-26.6%) and 15.3% died in an inpatient palliative care unit (95% confidence interval, 11.6%-19.5%). Management pathway and living circumstances were most strongly associated with place of death. Patients on the conservative pathway had four times the odds of dying out of hospital (odds ratio, 4.0; 95% confidence interval, 2.1-7.5; p < 0.01). Patients living alone were less likely to die out of hospital (odds ratio, 0.3; 95% confidence interval, 0.1-0.6; p < 0.01). There were also changes in place of death over time, with more patients dying out of hospital in 2012 compared to 2006 (odds ratio, 3.1; 95% confidence interval, 1.0-9.7; p < 0.05).
Most patients with end-stage kidney disease die in hospital, but patients managed without dialysis are significantly more likely to die outside of hospital. Planning ahead is key to be able to meet preference for place of death.
满足死亡地点偏好是临终关怀质量的一项重要指标。系统评价显示,42%的终末期肾病患者倾向于在家中离世。关于死亡地点的研究较少。
了解英国某一肾脏科已知的终末期肾病患者的死亡地点模式。
对2006年至2012年间死亡的所有慢性肾脏病4-5期、年龄≥75岁且在英国某一肾脏科就诊的患者进行回顾性队列研究。患者被分为三种管理途径:血液透析、保守治疗和透析前治疗。
共有321名患者(平均年龄82.7岁;标准差5.21)死亡(男性占61.7%)。总体而言,62.9%的患者在医院死亡(95%置信区间为57.5%-68.1%),21.8%的患者在其常住地死亡(95%置信区间为17.5%-26.6%),15.3%的患者在住院姑息治疗病房死亡(95%置信区间为11.6%-19.5%)。管理途径和生活状况与死亡地点的关联最为密切。接受保守治疗的患者在院外死亡的几率是其他患者的四倍(优势比为4.0;95%置信区间为2.1-7.5;p<0.01)。独居患者在院外死亡的可能性较小(优势比为0.3;95%置信区间为0.1-0.6;p<0.01)。随着时间推移,死亡地点也有所变化,与2006年相比,2012年在院外死亡的患者更多(优势比为3.1;95%置信区间为1.0-9.7;p<0.05)。
大多数终末期肾病患者在医院死亡,但未接受透析治疗的患者在院外死亡的可能性显著更高。提前规划是满足死亡地点偏好的关键。