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随机分配至瑜伽组或标准护理组的慢性下背痛患者的心率变异性

Heart rate variability in chronic low back pain patients randomized to yoga or standard care.

作者信息

Telles Shirley, Sharma Sachin Kumar, Gupta Ram Kumar, Bhardwaj Abhishek Kumar, Balkrishna Acharya

机构信息

Patanjali Research Foundation, Patanjali Yogpeeth, Haridwar, Uttarakhand, 249402, India.

出版信息

BMC Complement Altern Med. 2016 Aug 11;16(1):279. doi: 10.1186/s12906-016-1271-1.

Abstract

BACKGROUND

Chronic pain can alter the autonomic balance with increased sympathetic activity reflected in altered heart rate variability (HRV). It has been proposed that yoga can be useful to correct the autonomic imbalance in patients with chronic pain who have reduced HRV.

METHODS AND DESIGNS

In the present randomized controlled trial 62 patients with chronic low back pain associated with altered alignment of intervertebral discs (aged between 20 and 45 years, 32 males) were randomized to 2 groups. One group received yoga for 3 months while the other group carried out standard medical care based on the physician's advice. The duration was the same, i.e., 3 months. The heart rate variability and rate of respiration were assessed at baseline and at the end of 3 months.

RESULTS

There was a significant difference in the baseline (pre) values between groups (p = 0.008) for respiration rate which was higher in the yoga group. The changes reported below are pre-post comparisons within each group. The yoga group showed a significant (p < 0.05; repeated measures ANOVA, post-hoc analyses) decrease in the LF power of HRV, rate of respiration and a significant increase in the HF power of HRV and in the pNN50.

CONCLUSION

The results suggest that yoga practice can shift the autonomic balance towards vagal dominance in patients with chronic low back pain associated with altered alignment of intervertebral discs.

TRIAL REGISTRATION

The study is registered with the Clinical Trials Registry of India ( CTRI/2012/11/003094 ) and can be accessed at.

摘要

背景

慢性疼痛可改变自主神经平衡,增加的交感神经活动反映在心率变异性(HRV)改变上。有人提出,瑜伽可能有助于纠正HRV降低的慢性疼痛患者的自主神经失衡。

方法与设计

在本随机对照试验中,62例因椎间盘排列改变而患有慢性下腰痛的患者(年龄在20至45岁之间,男性32例)被随机分为两组。一组接受为期3个月的瑜伽训练,另一组根据医生建议进行标准医疗护理。持续时间相同,即3个月。在基线和3个月末评估心率变异性和呼吸频率。

结果

两组间呼吸频率的基线(术前)值存在显著差异(p = 0.008),瑜伽组更高。以下报告的变化是每组内术前与术后的比较。瑜伽组HRV的低频功率、呼吸频率显著降低(p < 0.05;重复测量方差分析,事后分析),HRV的高频功率和pNN50显著增加。

结论

结果表明,瑜伽练习可使因椎间盘排列改变而患有慢性下腰痛的患者的自主神经平衡向迷走神经优势转变。

试验注册

该研究已在印度临床试验注册中心注册(CTRI/2012/11/003094),可在……查阅。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf6d/4982400/346d17df8eb3/12906_2016_1271_Fig1_HTML.jpg

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