杨反应的过去、现在与未来。
The past, present, and future of the Yang reaction.
作者信息
Chen Chuo
机构信息
Department of Biochemistry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9038, USA.
出版信息
Org Biomol Chem. 2016 Oct 7;14(37):8641-7. doi: 10.1039/c6ob01214k. Epub 2016 Aug 12.
Abstract
Photoexcited ketones have diradical characteristics and are functionally similar to high-spin metal-oxo species that are frequently used to catalyze C-H oxidation. First discovered by Yang in 1958, photoexcited ketones can abstract a hydrogen atom from hydrocarbons inter- or intramolecularly. Coupling with atom-transfer, group-transfer, or radical addition, the Yang reaction can be used to achieve various types of C-H functionalization. We provide in this article an overview of triplet ketone-mediated or catalyzed C-H functionalization reactions.
摘要
光激发酮具有双自由基特征，在功能上类似于常用于催化C-H氧化的高自旋金属氧物种。光激发酮于1958年首次由杨发现，它可以从分子间或分子内的碳氢化合物中提取一个氢原子。通过与原子转移、基团转移或自由基加成反应相结合，杨反应可用于实现各种类型的C-H官能团化。我们在本文中概述了三重态酮介导或催化的C-H官能团化反应。
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