Department of Inorganic Chemistry, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland.
Department of Food Process Engineering, Lublin University of Life Sciences, 44 Doświadczalna Street, 20-236 Lublin, Poland.
Biomed Pharmacother. 2016 Oct;83:912-929. doi: 10.1016/j.biopha.2016.07.058. Epub 2016 Aug 10.
Photodynamic therapy (PDT) is an intensively studied part of medicine based on free radicals. These reactive species, extremely harmful for whole human organism, are used for eradication numerous diseases. Specific structure of ill tissues causes accumulation free radicals inside them without attack remaining healthy tissues. A rapid development of medicine and scientific research has led to extension of PDT towards treatment many diseases such as cancer, herpes, acne and based on antimicrobials. The presented review article is focused on the aforementioned disorders with accurate analysis of the newest available scientific achievements. The discussed cases explicitly indicate on high efficacy of the therapy. In most cases, free radicals turned out to be solution of many afflictions. Photodynamic therapy can be considered as promising treatment with comparable effectiveness but without side effects characteristic for chemotherapy.
光动力疗法（PDT）是医学中一个基于自由基的深入研究领域。这些反应性物质对整个人体组织极其有害，但被用于治疗许多疾病。病变组织的特定结构导致自由基在其内部积累，而不会攻击剩余的健康组织。医学和科学研究的快速发展使得 PDT 扩展到治疗许多疾病，如癌症、疱疹、痤疮和基于抗菌药物的疾病。本文综述文章集中在上述疾病上，并对最新的可用科学成果进行了准确分析。所讨论的病例明确表明了该疗法的高疗效。在大多数情况下，自由基被证明是许多疾病的解决方案。光动力疗法可以被认为是一种有前途的治疗方法，其疗效相当，但没有化疗的副作用。
