2019 年酒精与免疫学研究兴趣小组（AIRIG）会议总结：酒精导致多器官损伤的机制。
Summary of the 2019 alcohol and immunology research interest group (AIRIG) meeting: Alcohol-mediated mechanisms of multiple organ injury.
机构信息
Department of Surgery, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA; Alcohol Research Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Division of Pulmonary and Critical Care Medicine, Loyola University Chicago Health Sciences Campus, Maywood, IL, USA; Alcohol Research Program, Burn and Shock Trauma Research Institute, Loyola University Chicago Health Sciences Campus, Maywood, IL, USA.
出版信息
Alcohol. 2020 Sep;87:89-95. doi: 10.1016/j.alcohol.2020.04.008. Epub 2020 Apr 28.
On November 15, 2019, the 24th annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held as a satellite conference during the annual Society for Leukocyte Biology meeting in Boston, Massachusetts. The 2019 meeting focused on alcohol, immunity, and organ damage, and included two plenary sessions. The first session highlighted new research exploring the mechanisms of alcohol-induced inflammation and liver disease, including effects on lipidomics and lipophagy, regulatory T cells, epigenetics, epithelial cells, and age-related changes in the gut. The second session covered alcohol-induced injury of other organs, encompassing diverse areas of research ranging from neurodegeneration, to lung barrier function, to colon carcinogenesis, to effects on viral infection. The discussions also highlighted current laboratory and clinical research used to identify biomarkers of alcohol use and disease.
2019 年 11 月 15 日，第 24 届年度酒精与免疫学研究兴趣小组（AIRIG）会议在马萨诸塞州波士顿举行的白细胞生物学学会年会上作为卫星会议举行。2019 年会议的重点是酒精、免疫和器官损伤，并包括两个全体会议。第一个会议重点介绍了新的研究，探讨了酒精引起的炎症和肝病的机制，包括对脂质组学和脂自噬、调节性 T 细胞、表观遗传学、上皮细胞以及肠道中与年龄相关的变化的影响。第二个会议涵盖了酒精引起的其他器官损伤，涉及从神经退行性变、肺屏障功能、结肠癌发生到对病毒感染的影响等多个研究领域。讨论还强调了目前用于识别酒精使用和疾病生物标志物的实验室和临床研究。
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