Song Guang, Liu Jing, Qiao Wei, Chen Yixin, Sun Lu, Ren Weidong, Li Fangfang, Fan Miao
Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
Department of Obstetrics, First Affiliated Hospital of China Medical University, Shenyang, China.
Int J Cardiovasc Imaging. 2016 Dec;32(12):1687-1695. doi: 10.1007/s10554-016-0960-7. Epub 2016 Aug 18.
As the number of implanted biventricular pacemakers increases, the coronary sinus (CS) has evoked much interest amongst cardiologists. A dilated CS could prompt the existence of many diseases. The normal CS diameter is uncertain, especially in children. A total of 446 Chinese healthy children were prospectively enrolled in this study. The superior and inferior diameter of the CS was measured from the CS ostium 1 cm from the end of ventricular systole in the modified apical 4-chamber view. Seven models were tested to determine the relationships between parameters of body size and CS diameter. Heteroscedasticity was tested by the White and Breusch-Pagan tests. A multiple linear regression model should be gender as a covariate along with BSA, in order to evaluate the influence of gender on the measurements. The formula of Stevenson was best-fit. The predicted values and Z-score boundaries for measurement of the CS diameter were calculated. Bland-Altman plot regression showed that the 95 % limits of agreement for inter- and intra-observer measurements were not significantly different. We report new, reliable echocardiographic Z scores for the CS diameter derived from a large population of healthy Chinese children. The Z scores can be used in echocardiographic examinations.
随着植入式双心室起搏器数量的增加，冠状窦（CS）引起了心脏病专家的广泛关注。冠状窦扩张可能提示多种疾病的存在。正常冠状窦直径尚无定论，尤其是在儿童中。本研究前瞻性纳入了446名中国健康儿童。在改良心尖四腔视图中，于心室收缩末期距冠状窦口1 cm处测量冠状窦的上下径。测试了7种模型以确定身体大小参数与冠状窦直径之间的关系。通过怀特检验和布罗施-帕甘检验检测异方差性。为了评估性别对测量结果的影响，应将性别作为协变量纳入多元线性回归模型，同时纳入体表面积（BSA）。史蒂文森公式拟合效果最佳。计算了冠状窦直径测量的预测值和Z评分界限。布兰德-奥特曼图回归显示，观察者间和观察者内测量的95%一致性界限无显著差异。我们报告了来自大量中国健康儿童的可靠的冠状窦直径超声心动图Z评分。这些Z评分可用于超声心动图检查。
