Kang Eun Kyoung, Park Hee Won, Baek Sora, Lim Jae Young
Center for Farmers' Safety and Health and Department of Rehabilitation Medicine, Kangwon National University Hospital, Chuncheon, Korea.
Department of Rehabilitation Medicine, School of Medicine, Kangwon National University, Chuncheon, Korea.
J Korean Med Sci. 2016 Oct;31(10):1595-603. doi: 10.3346/jkms.2016.31.10.1595.
The purpose of this study was proposed to identify the association of trunk body composition with spinal bone mineral density (BMD) in Korean male and female farmers. A total of 523 Korean farmers (259 males, 44 premenopausal females, and 220 postmenopausal females) were recruited. Computed tomography scans were acquired at the mid-L4 vertebral level, and total trunk muscle mass (TMM, cm³), back muscle mass (BMM), and abdominal wall muscle mass (AMM), total trunk fat mass (TFM), visceral fat mass (VFM), and subcutaneous fat mass (SFM) were assessed. Spinal BMD (g/cm²) was estimated from dual-energy X-ray absorptiometry at the L4 level. In terms of muscle mass, spinal BMD was significantly correlated with all the components of the trunk muscle mass (r = 0.171-0.360; P < 0.05, P < 0.001) in female farmers, while only with AMM (r = 0.181; P < 0.01) in male farmers. In terms of fat mass, spinal BMD was significantly correlated with all components of the trunk fat mass (r = 0.142-0.424; P < 0.05, P < 0.001) in male and premenopausal female farmers, while only with VFM (r = 0.132; P < 0.05) in postmenopausal females. Adjusted multivariate regression analysis showed that AMM in male and post-menopausal female farmers was closely associated with spinal BMD. There may be positive associations between trunk muscle and fat mass and spinal BMD with sexual dimorphism, and abdominal wall muscle mass was an explanatory variable closely related to spinal BMD in Korean farmers. Registered at the Clinical Research Information Service (CRIS, http://cris.nih.go.kr), number KCT0000829.
本研究旨在确定韩国男性和女性农民躯干身体成分与脊柱骨密度（BMD）之间的关联。共招募了523名韩国农民（259名男性、44名绝经前女性和220名绝经后女性）。在L4椎体中部水平进行计算机断层扫描，并评估总躯干肌肉量（TMM，cm³）、背部肌肉量（BMM）和腹壁肌肉量（AMM）、总躯干脂肪量（TFM）、内脏脂肪量（VFM）和皮下脂肪量（SFM）。通过双能X线吸收法在L4水平估计脊柱BMD（g/cm²）。在肌肉量方面，女性农民的脊柱BMD与躯干肌肉量的所有组成部分均显著相关（r = 0.171 - 0.360；P < 0.05，P < 0.001），而男性农民仅与AMM相关（r = 0.181；P < 0.01）。在脂肪量方面，男性和绝经前女性农民的脊柱BMD与躯干脂肪量的所有组成部分均显著相关（r = 0.142 - 0.424；P < 0.05，P < 0.001），而绝经后女性仅与VFM相关（r = 0.132；P < 0.05）。调整后的多变量回归分析表明，男性和绝经后女性农民的AMM与脊柱BMD密切相关。躯干肌肉和脂肪量与脊柱BMD之间可能存在具有性别差异的正相关，并且腹壁肌肉量是与韩国农民脊柱BMD密切相关的一个解释变量。在临床研究信息服务中心（CRIS，http://cris.nih.go.kr）注册，编号KCT0000829。
