Wolters Anna, de Wert Guido, van Schayck Onno C P, Horstman Klasien
Maastricht University, School CAPHRI, Department of Health, Ethics, and Society.
Maastricht University, School CAPHRI, Department of General Practice.
Public Health Ethics. 2016 Jul;9(2):183-197. doi: 10.1093/phe/phw004. Epub 2016 Mar 14.
Experimental vaccines are being developed for the treatment of 'unhealthy lifestyles' and associated chronic illnesses. Policymakers and other stakeholders will have to deal with the ethical issues that this innovation path raises: are there morally justified reasons to integrate these innovative biotechnologies in future health policies? Should public money be invested in further research? Focusing on the case of an experimental nicotine vaccine, this article explores the ethical aspects of 'lifestyle vaccines' for public health. Based on findings from a qualitative study into a vaccine for smoking cessation, the article articulates possible value conflicts related to nicotine vaccination as an intervention in tobacco control. The 'vaccinization' of lifestyle disease piggybacks on the achievements of classic vaccines. Contrary to expectations of simplicity and success, quitting smoking with a vaccine requires a complex supportive network. Social justice and public trust may become important ethical challenges when deciding whether to use further public funds for research or whether to implement these innovative vaccines in the future.
正在研发用于治疗“不健康生活方式”及相关慢性病的实验性疫苗。政策制定者和其他利益相关者将不得不应对这一创新路径引发的伦理问题:是否有道德上合理的理由将这些创新生物技术纳入未来的卫生政策?是否应将公共资金投入进一步研究?本文以一种实验性尼古丁疫苗为例,探讨了“生活方式疫苗”对公共卫生的伦理层面。基于一项针对戒烟疫苗的定性研究结果,本文阐述了与尼古丁疫苗作为烟草控制干预措施相关的可能价值冲突。生活方式疾病的“疫苗接种”借助了经典疫苗的成果。与简单成功的预期相反,使用疫苗戒烟需要一个复杂的支持网络。在决定是否使用更多公共资金进行研究或未来是否实施这些创新疫苗时,社会正义和公众信任可能会成为重要的伦理挑战。