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偏头痛发作时中性粒细胞/淋巴细胞比值的变化:一项病例对照研究。

The change of neutrophils/lymphocytes ratio in migraine attacks: A case-controlled study.

作者信息

Karabulut Keziban Ucar, Egercioglu Tomris Ugur, Uyar Mehmet, Ucar Yildiz

机构信息

Department of Emergency Medicine, Baskent University, Faculty of Medicine, Ankara, Turkey.

Department of Neurology, Baskent University, Faculty of Medicine, Ankara, Turkey.

出版信息

Ann Med Surg (Lond). 2016 Jul 27;10:52-6. doi: 10.1016/j.amsu.2016.07.023. eCollection 2016 Sep.

Abstract

OBJECTIVE

As commonly seen symptoms, headaches are among the most frequently encountered health challenges in emergency rooms by healthcare professionals. Among one of the most commonly seen and primary headaches is migraine. Migraines are mostly accompanied by functional deficits.

AIMS

To observe the changes of neutrophil/lymphocyte ratio occurring during migraine attacks.

METHOD

This is a retrospective study where hospital records of patients previously diagnosed with migraine and admitted to the emergency with the complaints of attacks between May 2014 and January 2015 were investigated. All patients in the study were evaluated as to age, gender and complete blood count. Additionally, a healthy control group was formed with individuals with no disorders. By also evaluating the same features in the controls, the values found in the patients and controls alike were compared.

RESULTS

The values of white blood cell, lymphocyte, neutrophil, hemoglobin, thrombocyte and neutrophil/lymphocyte ratio determined in the patient group (n = 92) were statistically compared with those of the controls (n = 67). Neutrophil/lymphocyte ratio during the attacks was found higher in the patients, compared to the controls.

CONCLUSION

Neutrophil/lymphocyte ratio is a sign of inflammation, and we consider that this ratio will also increase during migraine attacks, as with other inflammatory and acute processes.

摘要

目的

头痛作为常见症状,是医疗专业人员在急诊室最常遇到的健康挑战之一。最常见的原发性头痛类型之一是偏头痛。偏头痛大多伴有功能缺陷。

目的

观察偏头痛发作期间中性粒细胞/淋巴细胞比值的变化。

方法

这是一项回顾性研究,调查了2014年5月至2015年1月期间因偏头痛发作而入院急诊的患者的医院记录。研究中的所有患者均就年龄、性别和全血细胞计数进行了评估。此外,以无疾病的个体组成一个健康对照组。通过评估对照组的相同特征,对患者和对照组中发现的值进行比较。

结果

将患者组(n = 92)中测定的白细胞、淋巴细胞、中性粒细胞、血红蛋白、血小板和中性粒细胞/淋巴细胞比值与对照组(n = 67)的这些值进行统计学比较。发现患者发作期间的中性粒细胞/淋巴细胞比值高于对照组。

结论

中性粒细胞/淋巴细胞比值是炎症的一个指标,并且我们认为与其他炎症和急性过程一样,在偏头痛发作期间这个比值也会升高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ad7/4983641/d9bfb92f252d/gr1.jpg

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