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提高阿拉伯联合酋长国成年糖尿病患者的药物依从性。

Improving adherence to medication in adults with diabetes in the United Arab Emirates.

作者信息

Al-Haj Mohd Mohammed M M, Phung Hai, Sun Jing, Morisky Donald E

机构信息

School of Public Health, Griffith University, Gold Coast, Australia.

Dubai Police Health Centre, Dubai, United Arab Emirates.

出版信息

BMC Public Health. 2016 Aug 24;16(1):857. doi: 10.1186/s12889-016-3492-0.

Abstract

BACKGROUND

Diabetes is a chronic medical condition and adherence to medication in diabetes is important. Improving medication adherence in adults with diabetes would help prevent the chronic complications associated with diabetes. A case control trial was used to study the effects of an educational session on medication adherence among adults with diabetes as measured by the Morisky Medication adherence scale (MMAS-8©).

METHODS

The study took place at the Dubai Police Health Centre between February 2015 and November 2015. Questionnaires were used to collect socio-demographic, clinical and disease related variables and the primary measure of outcome was adherence levels as measured by the Morisky Medication Adherence Scale (MMAS-8©). The intervention group involved a standardized thirty minute educational session focusing on the importance of adherence to medication. The change in MMAS-8© was measured at 6 months.

RESULTS

Four hundred and forty six patients were enrolled. Mean age 61 year +/- 11. 48.4 % were male. The mean time since diagnosis of diabetes was 3.2 years (Range 1-15 years). At baseline two hundred and eighty eight (64.6 %) patients were considered non-adherent (MMAS-8© adherence score < 6) while 118 (26.5 %) and 40 (9.0 %) had low adherence (MMAS-8© adherence score < 6) and medium adherence (MMAS-8© adherence scores of 6 to 7) to their medication respectively. The percentage of patients scoring low adherence MMAS-8 scores in the interventional group dropped from 64.60 % at baseline to 44.80 % at 6-months (p = 0.01). There was no obvious change in the adherence scores at baseline and at 6-months in the control group. Based on the study data, the Wilcoxon signed-rank test showed that at 6 months, the educational 30-min session on diabetes and adherence to medication did elicit a statistically significant change in adherence levels in adults with diabetes enrolled in the intervention arm (Z = -6.187, p <0.001).

CONCLUSION

Adults with diabetes would benefit from educational sessions focusing on the importance of adherence to medication. Public health strategies should focus on wider educational strategies targeting medication adherence in diabetic patients in the UAE.

摘要

背景

糖尿病是一种慢性疾病,糖尿病患者坚持服药很重要。提高成年糖尿病患者的服药依从性有助于预防与糖尿病相关的慢性并发症。本研究采用病例对照试验,通过莫氏药物依从性量表(MMAS - 8©)来研究一场教育讲座对成年糖尿病患者药物依从性的影响。

方法

该研究于2015年2月至2015年11月在迪拜警察健康中心开展。通过问卷调查收集社会人口统计学、临床及疾病相关变量,主要结局指标是用莫氏药物依从性量表(MMAS - 8©)测量的依从性水平。干预组接受一场30分钟的标准化教育讲座,重点讲解坚持服药的重要性。在6个月时测量MMAS - 8©的变化。

结果

共纳入446名患者。平均年龄61岁±11岁。48.4%为男性。糖尿病确诊后的平均时间为3.2年(范围1 - 15年)。基线时,288名(64.6%)患者被认为不依从(MMAS - 8©依从性得分<6),而118名(26.5%)和40名(9.0%)患者分别对药物治疗的依从性低(MMAS - 8©依从性得分<6)和中等(MMAS - 8©依从性得分为6至7)。干预组中MMAS - 8得分低依从性的患者百分比从基线时的64.60%降至6个月时的44.80%(p = 0.01)。对照组在基线和6个月时的依从性得分无明显变化。根据研究数据,Wilcoxon符号秩检验显示,在6个月时,这场关于糖尿病和坚持服药的30分钟教育讲座确实使干预组成年糖尿病患者的依从性水平发生了具有统计学意义的变化(Z = -6.187,p<0.001)。

结论

成年糖尿病患者将从关注坚持服药重要性的教育讲座中受益。公共卫生策略应侧重于针对阿联酋糖尿病患者服药依从性的更广泛教育策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e275/4995640/a01752267e24/12889_2016_3492_Fig1_HTML.jpg

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