Department of Preventive and Community Dentistry, School of Dentistry, Pusan National University, 49 Busandaehak-ro, Mulgeum-eup Yangsan, Gyeongsangnam-do 626-870, Korea.
BK21 PLUS Project, School of Dentistry, Pusan National University, 49 Busandaehak-ro, Mulgeum-eup Yangsan, Gyeongsangnam-do 626-870, Korea.
Int J Environ Res Public Health. 2019 Aug 15;16(16):2930. doi: 10.3390/ijerph16162930.
This study aimed to evaluate the association between periodontitis and metabolic syndrome (MetS) and to investigate risk factors associated with MetS in Korean adults aged 35 to 79 years. Among individuals aged 35-79 years who participated in the Korea National Health and Nutrition Examination Survey 2013-2015, 8314 participants who completed the required examinations and questionnaires were included. Confounding variables related to demographic and socioeconomic status and systemic and oral health-related behaviors were age, gender, household income, education level, smoking, alcohol intake, physical activity, and frequency of daily toothbrushing. Of the 8314 participants, 32.2% were diagnosed with MetS. The prevalence of MetS was 26.6% and 41.6% in those without and with periodontitis, respectively. Among individuals with periodontitis, the prevalence of MetS was 44.3% in males and 36.9% in females. Compared to non-periodontitis, periodontitis was associated with MetS (adjusted OR = 1.422, 95% CI: 1.26-1.61). Age, frequency of daily toothbrushing, and periodontitis were associated with MetS in both males and females. While current smoking and alcohol intake more than twice a week were significantly associated with MetS in males, household income and education level were significantly associated with MetS in females. The findings suggest that periodontitis can be associated with MetS.
本研究旨在评估牙周炎与代谢综合征（MetS）之间的关联，并探讨韩国 35 至 79 岁成年人发生代谢综合征的相关危险因素。在参与了 2013-2015 年韩国国家健康和营养调查的 35-79 岁人群中，纳入了完成必需检查和问卷调查的 8314 名参与者。与人口统计学和社会经济状况以及全身和口腔健康相关行为有关的混杂变量包括年龄、性别、家庭收入、教育水平、吸烟、饮酒、身体活动和每日刷牙频率。在 8314 名参与者中，32.2%被诊断为代谢综合征。无牙周炎和有牙周炎者的代谢综合征患病率分别为 26.6%和 41.6%。在有牙周炎的人群中，男性的代谢综合征患病率为 44.3%，女性为 36.9%。与非牙周炎相比，牙周炎与代谢综合征相关（调整后的 OR=1.422，95%CI：1.26-1.61）。年龄、每日刷牙频率和牙周炎与男性和女性的代谢综合征均相关。而男性中当前吸烟和每周饮酒两次以上与代谢综合征显著相关，女性中家庭收入和教育水平与代谢综合征显著相关。研究结果表明，牙周炎可能与代谢综合征有关。
