Ferrell B, Wisdom C, Wenzl C, Brown J
Oncol Nurs Forum. 1989 Jul-Aug;16(4):521-6.
Oncology nursing is concerned with pain relief and overall Quality of Life (QOL). The purpose of this study was to determine the effects of controlled-release morphine on QOL for patients with cancer. Eighty-three subjects were randomly assigned in a clinical trial of short-acting versus controlled-release analgesia (MS Contin, Purdue Frederick Co., Norwalk, CT). Data was collected in a repeated measures design every 2 weeks for 6 weeks yielding a total of 240 visits. Five instruments were used to assess QOL, pain, and functional status. Study findings indicate improved pain management with controlled-release MS Contin and important nursing implications for the management of analgesia-induced gastrointestinal symptoms. Through appropriate pain management with pain therapies such as controlled-release analgesia, nurses can greatly enhance QOL for the patient with cancer.
肿瘤护理关注疼痛缓解和总体生活质量（QOL）。本研究的目的是确定控释吗啡对癌症患者生活质量的影响。83名受试者被随机分配到一项短效与控释镇痛的临床试验中（美施康定，普渡弗雷德里克公司，诺沃克，康涅狄格州）。采用重复测量设计，每2周收集一次数据，为期6周，共进行240次访视。使用了五种工具来评估生活质量、疼痛和功能状态。研究结果表明，使用控释美施康定可改善疼痛管理，并且对镇痛引起的胃肠道症状的管理具有重要的护理意义。通过使用控释镇痛等疼痛治疗方法进行适当的疼痛管理，护士可以极大地提高癌症患者的生活质量。
