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硫化锌纳米颗粒在不同生物应用中的作用洞察。

Insight of ZnS nanoparticles contribution in different biological uses.

作者信息

Labiadh Houcine, Lahbib Karima, Hidouri Slah, Touil Soufiane, Chaabane Tahar Ben

机构信息

Unité de Recherche UR11ES30 de Synthèse et Structures de Nanomatériaux, Faculté des Sciences de Bizerte, 7021 Jarzouna, Tunisia.

Laboratory of Heteroatom Organic Chemistry, Department of Chemistry, Faculty of Sciences of Bizerte, Carthage University, 7021 Jarzouna, Tunisia.

出版信息

Asian Pac J Trop Med. 2016 Aug;9(8):757-62. doi: 10.1016/j.apjtm.2016.06.008. Epub 2016 Jun 29.

Abstract

OBJECTIVES

To evaluate the contributions of the some quantum dots in different biological uses in order to valorizes such nanomaterials for further applications.

METHODS

Zinc sulfide ZnS nanoparticles were synthesized in aqueous medium at pH constant, the obtained nanoparticles has been characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and Fourier Transform Infra-red (FTIR) spectroscopies. Zinc sulfide nanoparticles were screened for their antibacterial and antifungal profiling and tested for antioxidant activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical (OH) and hydrogen peroxide (H2O2) scavenging activity, ferric reducing power (FRP) assay and ferrous ion chelating (FIC) methods.

RESULTS

The sizes of the crystallites were estimated to 3 nm using the Debye-Scherrer formula based on the XRD data. The shape was identified to be quasi-spherical with agglomerated particles. The obtained ZnS quantum dots present an antioxidant activity especially in oxido-reduction power, and can be used for species profiling either for bacteria and fungus.

CONCLUSION

It was found that ZnS nanoparticles showed relatively higher antioxidant activities and antibacterial with an antifungal behavior which proves that this nanomaterials can react at the interface with the life entities.

摘要

目的

评估某些量子点在不同生物用途中的贡献,以便使此类纳米材料具有更高价值以用于进一步应用。

方法

在恒定pH的水性介质中合成硫化锌(ZnS)纳米颗粒,通过X射线衍射(XRD)、透射电子显微镜(TEM)和傅里叶变换红外(FTIR)光谱对所得纳米颗粒进行表征。对硫化锌纳米颗粒进行抗菌和抗真菌分析筛选,并使用1,1 - 二苯基 - 2 - 苦基肼(DPPH)、羟基自由基(OH)和过氧化氢(H2O2)清除活性、铁还原能力(FRP)测定和亚铁离子螯合(FIC)方法测试其抗氧化活性。

结果

根据XRD数据使用德拜 - 谢乐公式估计微晶尺寸为3纳米。形状被确定为准球形且颗粒团聚。所获得的ZnS量子点具有抗氧化活性,特别是在氧化还原能力方面,并且可用于细菌和真菌的物种分析。

结论

发现ZnS纳米颗粒表现出相对较高的抗氧化活性以及抗菌和抗真菌行为,这证明这种纳米材料可以在与生命实体的界面处发生反应。

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