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Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
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Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool.
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Synaptic proteins that aggregate and degrade slower with aging accumulate in microglia.
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Imaging and manipulating proteins in live cells through covalent labeling.
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Expanding and reprogramming the genetic code of cells and animals.
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Site-specific protein labeling using PRIME and chelation-assisted click chemistry.
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Expanding the genetic code for photoclick chemistry in E. coli, mammalian cells, and A. thaliana.
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A Gq-Ca2+ axis controls circuit-level encoding of circadian time in the suprachiasmatic nucleus.
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Expanding the genetic code of Drosophila melanogaster.
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