Becker U, Tønnesen H, Kaas-Claesson N, Gluud C
Medical Department, Hvidovre University Hospital, Copenhagen, Denmark.
Drug Alcohol Depend. 1989 Aug;24(1):75-82. doi: 10.1016/0376-8716(89)90012-4.
Data on menstrual pattern, gynecological disorders and infertility were obtained from 51 chronic alcoholic women aged 20--42 years attending an outpatient clinic for alcoholics, using 51 randomly drawn age-matched healthy women as controls. A higher variability (P less than 0.05) in the duration of both menstrual cycle and menstrual flow was recorded in the chronic alcoholic women during active alcoholism. A higher frequency (P less than 0.05) of menstrual disturbances (70% vs. 55%) and uterine curettages (38% vs. 16%) were found in the alcoholic women. The latter reported more abortions (63% vs. 28%, P less than 0.001) and miscarriages (23% vs. 8%, P less than 0.05) than controls, but due to a higher number of pregnancies in the alcoholic group the proportion of abortions and miscarriages did not differ significantly. No differences existed between the groups regarding frequency of difficult conception. Social classification had no independent influence on the results. The study shows that chronic alcoholic women are more prone to menstrual abnormalities and are at greater risk of gynecological interventions, while they do not seem to have reduced fertility.
关于月经模式、妇科疾病和不孕症的数据，是从51名年龄在20至42岁的慢性酒精中毒女性中获取的，这些女性在一家戒酒门诊就诊，同时选取了51名随机抽取的年龄匹配的健康女性作为对照。在慢性酒精中毒女性处于酒精成瘾活跃期时，记录到她们的月经周期和月经量的变异性更高（P<0.05）。在酒精成瘾女性中发现月经紊乱（70%对55%）和刮宫术（38%对16%）的发生率更高（P<0.05）。与对照组相比，酒精成瘾女性报告的堕胎（63%对28%，P<0.001）和流产（23%对8%，P<0.05）更多，但由于酒精成瘾组的怀孕次数较多，堕胎和流产的比例并无显著差异。两组在受孕困难频率方面没有差异。社会阶层分类对结果没有独立影响。该研究表明，慢性酒精中毒女性更容易出现月经异常，接受妇科干预的风险更高，而她们的生育能力似乎并未降低。
