Kim Tae-Hwan, Kim Chul-Hwan
Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University, Cheonan, Korea.
J Korean Assoc Oral Maxillofac Surg. 2016 Aug;42(4):221-6. doi: 10.5125/jkaoms.2016.42.4.221. Epub 2016 Aug 24.
Spindle cell carcinoma (SpCC) is referred to as a variant of oral squamous cell carcinoma. It is also known as "sarcomatoid squamous cell carcinoma" because it consists of normal squamous carcinoma cells with spindle-shaped cells that appear similar to a sarcoma. The term, "second primary tumor" (SPT) or "double primary tumor", is proposed for a second tumor that develops independently from the first. SPTs can present as either synchronous or metachronous lesions. Synchronous SPTs are defined as tumors occurring simultaneously or within 6 months after the first tumor. The patient in this case, whose primary tumor was in the tongue, was diagnosed with SpCC with metastases to both neck lymph nodes. This case also exhibited a second primary cancer as a synchronous lesion in the thyroid gland, which is uncommon. All carcinomas, both in the tongue and thyroid gland, were removed surgically, and especially in the tongue, an anterolateral thigh free flap was performed successfully to replace the defect.
梭形细胞癌（SpCC）被认为是口腔鳞状细胞癌的一种变体。它也被称为“肉瘤样鳞状细胞癌”，因为它由正常的鳞状癌细胞和类似肉瘤的梭形细胞组成。“第二原发肿瘤”（SPT）或“双原发肿瘤”这一术语用于指独立于第一肿瘤发生的第二肿瘤。SPT可表现为同时性或异时性病变。同时性SPT被定义为与第一肿瘤同时发生或在第一肿瘤发生后6个月内出现的肿瘤。该病例的原发肿瘤位于舌部，患者被诊断为伴有双侧颈部淋巴结转移的SpCC。该病例还表现出作为同时性病变的甲状腺第二原发癌，这并不常见。舌部和甲状腺的所有癌均通过手术切除，特别是在舌部，成功进行了股前外侧游离皮瓣移植以修复缺损。
